Cannabinoides en porros de resina de cannabis decomisados en Castilla y León
Abstract Fundamento: El cannabis, en sus productos hierba y resina, es la droga ilegal más consumida en el mundo. El…
Research Article
Toxicological evaluation and preliminary phytochemical characterisation of a Nigerian Cannabis sativa chemovar
Abstract Objective(s): Different Cannabis sativa chemovars produce diverse pharmacological and behavioral effects. With the widespread use of cannabis in Nigeria,…
Cannabigerol Treatment Shows Antiproliferative Activity and Causes Apoptosis of Human Colorectal Cancer Cells
Abstract Objectives: To determine growth inhibitory and anti-cancer effects of Cannabigerol (CBG) in human colorectal cancer cells. Methods: Anti-proliferative effect…
Prevalence and patterns of substance use in West Africa: A systematic review and meta-analysis
Abstract Introduction: Substance use is a growing public health concern in West Africa, contributing to significant morbidity, mortality, and socioeconomic…
Characterization of phenolic compounds and evaluation of anti-diabetic potential in Cannabis sativa L. seeds: In vivo, in vitro, and in silico studies
Abstract Moroccan Cannabis sativa L. seeds were investigated for their phenolic profile and antidiabetic potential. Ultra-high-performance liquid chromatography with diode…
The effects of plant density and duration of vegetative growth phase on agronomic traits of medicinal cannabis (Cannabis sativa L.): A regression analysis
Abstract Empirical data on the effect of plant density (PD) and length of the vegetative phase (DVP) on plant growth,…
Structure- and Ligand-Based Virtual Screening for Identification of Novel TRPV4 Antagonists
Abstract Transient receptor potential vanilloid (TRPV) 4 is involved in signaling pathways specifically mediating pain and inflammation, making it a…
Mitigating the Risk of QTc Prolongation When Using Haloperidol for Acute Treatment of Cannabinoid Hyperemesis Syndrome in Adolescents and Young Adults
Abstract Background/Objectives: Cannabinoid Hyperemesis Syndrome (CHS), associated with long-term cannabinoid use, has been increasingly observed in emergency room visits as…
Fenfluramine treatment for Dravet syndrome: Long term real‐world analysis demonstrates safety and reduced health care burden
Abstract Objective: Fenfluramine (FFA), stiripentol (STP), and cannabidiol (CBD) are approved add‐on therapies for seizures in Dravet syndrome (DS). We…
Pharmacokinetics and Side Effects of Δ9-Tetrahydrocannabinol and Cannabidiol in Patients with Different Stages of CKD
Abstract Introduction: Chronic kidney disease (CKD) affects approximately 10% of the global population and is associated with a large symptom…