Optimization of seizure prevention by cannabidiol (CBD)
Abstract Objective: Cannabidiol (CBD) is one of the most prominent non-psychotropic cannabinoids with known therapeutic potentials. Based on its anti-seizure…
Research Article
Cannabinerol Restores mRNA Splicing Defects Induced by β-Amyloid in an In Vitro Model of Alzheimer’s Disease: A Transcriptomic Study
Abstract Alzheimer’s disease (AD) is the most common form of dementia, characterized by β-amyloid (Aβ) plaques and neurofibrillary tangles, leading…
The Identification of Novel Anti-Inflammatory Effects of Cannabigerol in the Kidney Tissue of Rats Subjected to a High-Fat High-Sucrose Diet
Abstract The inflammatory state is a significant factor associated with diabetic kidney disease (DKD), making it one of the significant…
Lipopolysaccharide-binding protein (LBP): a prognostic biomarker for gastric cancer linked to immune infiltration
Abstract Background: Gastric cancer, characterized by rising global incidence and mortality, faces significant challenges due to the lack of effective…
A spatially resolved transcriptome landscape during thyroid cancer progression
Abstract Tumor microenvironment (TME) remodeling plays a pivotal role in thyroid cancer progression, yet its spatial dynamics remain unclear. In…
Comprehensive Pan-cancer Analysis Revealed CASP10 As a Promising Biomarker For Diverse Tumor Types
Abstract We aimed to explore the comprehensive cancer landscape of Caspase-10 (CASP10). CASP10, a member of the caspase family, is…
A Network-Based Approach Exploiting Transcriptomics and Interactomics Data for Predicting Drug Repurposing Solutions Across Human Cancers
Abstract Drug repurposing can be an effective way to identify potential therapies for various diseases. Biological networks can be useful…
ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling
Abstract Triple‐negative breast cancer (TNBC) is highly metastatic and presents clinical challenges given the lack of targeted therapies. Here, we…
Kazakhstani Drivers and Substance Abuse During COVID-19: A Study of Patterns and Disaster Readiness
Abstract Background/Objectives: The COVID-19 pandemic has significantly affected public health and social behavior, contributing to increased psychoactive substance (PAS) use…
Substance use among young people in the West Arsi Zone, Ethiopia: A cross-sectional study
Abstract Introduction: Substance use is a pressing public health concern in young Ethiopians, impacting their physical, psychosocial, and emotional well-being…