Effects of legal-market cannabis and alcohol on verbal learning and memory
Abstract Rationale: Widespread legalization of cannabis in the US in recent years has coincided with increasing use of alcohol and…
Research Article
Cannabinoid CB1 receptor and mu-opioid receptor interaction: new insights from conditional knockout mice
Abstract Co-administration of cannabinoids and opioids has been shown to enhance analgesic effects. However, the underlying mechanisms remain unclear. One…
Development of a disaster nursing training program for undergraduate interns in mobile cabin hospital settings
Abstract Objective: To develop a structured “Disaster Nursing Practice Week” training program for undergraduate nursing interns, tailored to the context…
Prevalence of AAS‐Positive Samples at Drug Abuse Laboratory Sweden Between 2014 and 2023 and Sub‐Study of Dual Use of AAS and Narcotics
Abstract It is of interest to investigate trends in AAS usage profile. Here we aimed to retrospectively study the prevalence…
Burden and trends of drug use disorders in young adults: global insights from GBD 2021
Abstract Background: Drug use disorders (DUDs) is a serious global health crisis, particularly affecting adolescents and young people. The increasing…
Cannabidiol Lipid Nanoparticles Stabilize Gut–Brain–Bone Axis Integrity and Enhance Neuroplasticity in Stressed Rats: A Comparison with Atomoxetine and Escitalopram
Abstract Chronic stress induces mood disturbances, disrupts gut barrier function, and promotes low-grade systemic inflammation. This study assessed the therapeutic…
Carvone derived cannabidiol enantiomers as novel anticonvulsants
Abstract Developmental epilepsy syndromes are characterized by recurrent seizures and developmental delays. Current anticonvulsants target γ-aminobutyric acid type A receptor…
Glycosylated cannabinoids in Cannabis sativa and enzyme design to modulate their synthesis
Abstract Cannabinoids are the primary active compounds in Cannabis sativa and hold significant medical potential. However, their high lipophilicity limits…
Cannabidiol reverses depression-like behaviors by enhancing hippocampal synaptic plasticity in rats with chronic restraint stress
Abstract Background and Aim: Major depressive disorder is a prevalent psychiatric condition associated with impaired neuroplasticity, particularly in the hippocampus.…
Optimization, Kinetics, and Thermodynamics of Ultrasound-Assisted Extraction of Phytochemicals from Hemp
Abstract Hemp (Cannabis sativa L.) is a rich source of bioactive compounds, yet efficient extraction strategies that maximize beneficial cannabidiol…