Influence of Cannabidiol Use on Visual Function and Optical Quality: A Randomized Controlled Trial
Abstract Purpose: To study the influence of different concentrations of vaporized cannabidiol (CBD; 0%, 15%, and 30%) on visual function…
Research Article
Rethinking Alzheimer’s: Harnessing Cannabidiol to Modulate IDO and cGAS Pathways for Neuroinflammation Control
Abstract Alzheimer’s disease (AD) has traditionally been associated with amyloid-β plaques, but growing evidence underscores the role of neuroinflammation in…
Cannabinoid CB1 receptor in dopaminergic circuit from ventral tegmental area to nucleus accumbens links trait anxiety with reward learning
Abstract The endocannabinoid (eCB) system has risen as a critical modulator linking the environmental challenges to behavioral maladaptation, such as…
Relevance of a peripheral site of action outside the brain-blood barrier for the beneficial effects of CB2 receptor activation in experimental ALS in male mice
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12964-025-02418-2. Article type: Research Article Keywords: Amyotrophic lateral sclerosis,…
Correlates of residential detoxification completers and non-completers in Alberta
Abstract Objectives: We aimed to identify factors correlated with completion, non-completion and cycling between completion and non-completion among clients admitted…
Cannabis use patterns and different phenotypes in relation to use of other drugs: latent class analyses from the São Paulo Megacity Mental Health Survey
Abstract Objective: Cannabis is the most widely used substance in Brazil. This study examined subtypes of individuals who use cannabis…
Risk of Heart Failure-related Events in Patients Exposed to Medical Cannabis: A Longitudinal Cohort Study
Abstract Objective: This study examined the association between the authorized prescription of cannabis and heart failure (HF) events. Study design:…
Patterns of Psychiatric Comorbidity Among Drug Users: A Prospective Observational Study in a Romanian Psychiatric Hospital
Abstract Background: A large number of substance use disorders are increasingly associated with complex clinical presentations and unknown mental and…
Association of preconception cannabis use frequency with cannabis use during early pregnancy
Abstract Background: Cannabis use during pregnancy is increasingly common and is associated with adverse health outcomes for pregnant individuals and…
Cannabigerol Modulates Cannabinoid Receptor Type 2 Expression in the Spinal Dorsal Horn and Attenuates Neuropathic Pain Models
Abstract Background/Objectives: The expanding focus on novel therapeutic pathways for long-term pain relief has directed interest toward compounds obtained from…