Endocannabinoid system and skeletal muscle health: Insights from cannabidiol
Abstract The endocannabinoid (EC) system is a complex network comprising endogenous ligands, enzymes responsible for their synthesis and degradation, and…
sarcopenia
Sarcopenia and cachexia: molecular mechanisms and therapeutic interventions
Abstract Sarcopenia is defined as a muscle‐wasting syndrome that occurs with accelerated aging, while cachexia is a severe wasting syndrome…
Managing Cachexia in Head and Neck Cancer: a Systematic Scoping Review
Abstract Introduction: Patients with head and neck cancer (HNC) are usually confronted with functional changes due to the malignancy itself…
The Clinical Value of Nutritional Care before and during Active Cancer Treatment
Abstract Malnutrition and muscle wasting are frequently reported in cancer patients, either linked to the tumor itself or caused by…
Pharmacological management of cachexia in adult cancer patients: a systematic review of clinical trials
Abstract Background: Cachexia is a multisystem syndrome characterized by weight loss, anorexia, loss of muscle mass, systemic inflammation, insulin resistance,…
Study Design and Rationale for the Phase 3 Clinical Development Program of Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials)
Abstract Muscle wasting in cancer is a common and often occult condition that can occur prior to overt signs of…