Pharmacokinetics of Cannabinoids Delivered by Diverse Routes in Rodents
Abstract Background: The rising popularity of medicinal and recreational use of Cannabis sativa L. has prompted a parallel increase in…
rodents
Interindividual and sex differences in resilience and vulnerability to post-traumatic stress disorder (PTSD): insights from animal models
Abstract Stress triggers many responses including behavioral strategies to cope with the environment and to maintain homeostasis. Notably, the experience…
Advances in understanding migraine pathophysiology: a bench to bedside review of research insights and therapeutics
Abstract The individual and global burden of migraine is of such significance that there are accelerated efforts to develop new…
Utility of the Zebrafish Model for Studying Neuronal and Behavioral Disturbances Induced by Embryonic Exposure to Alcohol, Nicotine, and Cannabis
Abstract It is estimated that 5% of pregnant women consume drugs of abuse during pregnancy. Clinical research suggests that intake…
Prenatal alcohol and tetrahydrocannabinol exposure: Effects on spatial and working memory
Abstract Introduction: Alcohol and cannabis are widely used recreational drugs that can negatively impact fetal development, leading to cognitive impairments.…
Novel GPR18 Ligands in Rodent Pharmacological Tests: Effects on Mood, Pain, and Eating Disorders
Abstract The lack of selective pharmacological tools has limited the full unraveling of G protein-coupled receptor 18 (GPR18) functions. The…
Behavioral effects on the offspring of rodent mothers exposed to Tetrahydrocannabinol (THC): A meta-analysis
Abstract Pre and perinatal administration of Tetrahydrocannabinol (THC) in rodents and their offspring has many effects that have been studied…
Biomarkers of the Endocannabinoid System in Substance Use Disorders
Abstract Despite substance use disorders (SUD) being one of the leading causes of disability and mortality globally, available therapeutic approaches…
Reactivation-Dependent Amnesia for Contextual Fear Memories: Evidence for Publication Bias
Abstract Research on memory reconsolidation has been booming in the last two decades, with numerous high-impact publications reporting promising amnestic…