Distinct involvement of the cranial and spinal nerves in progressive supranuclear palsy
Abstract The most frequent neurodegenerative proteinopathies include diseases with deposition of misfolded tau or α-synuclein in the brain. Pathological protein…
progressive supranuclear palsy
Progressive supranuclear palsy: A case report and brief review of the literature
Abstract Atypical Parkinsonian syndromes are a subset of progressive neurodegenerative disorders that present with signs of Parkinson’s disease. However, due…
Determinants of astrocytic pathology in stem cell models of primary tauopathies
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s40478-023-01655-1. Article type: Research Article Keywords: Astrocytes, Stem cells,…
Diagnostic accuracy of cerebral [18F]FDG PET in atypical parkinsonism
Abstract Background: Atypical parkinsonism (AP) often presents with Parkinson’s symptoms but has a much worse long-term prognosis. The diagnosis is…
Determinants of Astrocytic Pathology in Stem Cell Models of Primary Tauopathies
Abstract Astrocytic tau aggregates are seen in several primary and secondary tauopathies, including progressive supranuclear palsy (PSP), corticobasal degeneration (CBD),…
Neurological update: non-motor symptoms in atypical parkinsonian syndromes
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00415-023-11807-x. Article type: Research Article Keywords: Parkinson’s disease, Atypical…
Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s40478-023-01584-z. Article type: Case Report Keywords: Progressive supranuclear palsy,…
The evolution of diagnosis from symptom onset to death in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) compared to Parkinson’s disease (PD)
Abstract Background: Misdiagnosis and delayed diagnosis in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are common. Few studies have…
Midbrain and pons MRI shape analysis and its clinical and CSF correlates in degenerative parkinsonisms: a pilot study
Abstract Objectives: To conduct brainstem MRI shape analysis across neurodegenerative parkinsonisms and control subjects (CS), along with its association with…
Single-nucleus chromatin accessibility profiling highlights distinct astrocyte signatures in progressive supranuclear palsy and corticobasal degeneration
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00401-022-02483-8. Article type: Research Article Keywords: Progressive supranuclear palsy,…