Abstract Single-cell RNA sequencing (scRNA-seq) was used to dissect the cellular composition and gene expression patterns of thyroid cancer (THCA),…
Abstract Background: Methyltransferase-like (METTL) family protein plays a crucial role in the progression of malignancies. However, the function of METTL17…
Abstract Background: The ubiquitin-proteasome system (UPS) is vital for protein quality control and its dysregulation is linked to diseases, including…
Abstract Background: SEPT9 is a pivotal cytoskeletal GTPase that regulates diverse biological processes encompassing mitosis and cytokinesis. While previous studies…
Abstract Pyrroline-5-carboxylate reductase (PYCR) is pivotal in converting pyrroline-5-carboxylate (P5C) to proline, the final step in proline synthesis. Three isoforms,…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10238-024-01387-z. Article type: Research Article Keywords: Multi-omics analysis, Thyroid…
Abstract Objective: The primary objective of this study is to conduct a comprehensive screening and analysis of differentially expressed genes…
Abstract Objective: An mRNA expression-based stemness index (mRNAsi) has been developed to characterize cancer stemness. However, the predictive value of…
Abstract Thyroid cancer, notably papillary thyroid cancer (PTC), is a global health concern with increasing incidence. Anoikis, a regulator of…
Abstract Background: Thyroid cancer (THCA) is a common endocrine malignancy. This study aimed to explore the expression of pyroptosis-related genes…