Comprehensive pan-cancer analysis of ZNF337 as a potential diagnostic, immunological, and prognostic biomarker
Abstract Background: Zinc Finger Protein 337 (ZNF337) is a novel Zinc Finger (ZNF) protein family member. However, the roles of…
prognostic biomarker
MZT2A serves as a prognostic biomarker and promotes the progression of kidney renal clear cell carcinoma
Abstract MZT2A is a novel core component in the γ-tubulin ring complex and aberrantly expressed in some types of tumors.…
CCND1 as a Prognostic and Diagnostic Biomarker and the Impact of Its Epigenetic Alterations on Cancer Survival
Abstract Background: Cyclin D1 (CCND1) plays a crucial role in cell cycle regulation and has been implicated in various cancers.…
Coexisting RET/PTC and TERT Promoter Mutation Predict Poor Prognosis but Effective RET and MEK Targeting in Thyroid Cancer
Abstract Context: The role of RET/PTC rearrangement in the clinical outcomes of papillary thyroid cancer (PTC) is controversial and remains…
Comprehensive Pan-Cancer Analysis of Connexin 43 as a Potential Biomarker and Therapeutic Target in Human Kidney Renal Clear Cell Carcinoma (KIRC)
Abstract Background and Objectives: Connexin 43 (Cx43) is involved in the transfer of small signaling molecules between neighboring cells, thereby…
Identification of immune-associated biomarker for predicting lung adenocarcinoma: bioinformatics analysis and experiment verification of PTK6
Abstract Background: Abnormal expression of protein tyrosine kinase 6 (PTK6) has been proven to be involved in the development of…
Comprehensive Analysis Reveals Deoxyribonuclease 1 as a Potential Prognostic and Diagnostic Biomarker in Human Cancers
Abstract Background: Deoxyribonuclease 1 (DNASE1) is an important gene associated with several cancers, including liver, bladder, and gastric cancer. It…
4-Hydroxyphenylpyruvate Dioxygenase-Like predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis
Abstract The 4-Hydroxyphenylpyruvate Dioxygenase-Like (HPDL) protein plays a crucial role in safeguarding cells from oxidative stress by orchestrating metabolic reprogramming.…
Multicomponent comprehensive confirms that erythroferrone is a molecular biomarker of pan-cancer
Abstract All vertebrates organisms produce erythroferrone, a secretory hormone with structure-related functions during iron homeostasis. However, limited knowledge exists regarding…
MDM4 was associated with poor prognosis and tumor-immune infiltration of cancers
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s40001-024-01684-z. Article type: Research Article Keywords: MDM4, Pan-cancer, Prognostic…