Eye tracking as a digital biomarker in neurodegenerative diseases
Abstract Oculomotor abnormalities are a common finding in neurodegenerative diseases due to degeneration of neural pathways and brain regions involved…
Parkinson’s disease
Recent Preclinical Evidence on Phytocannabinoids in Neurodegenerative Disorders: A Focus on Parkinson’s and Alzheimer’s Disease
Abstract The endocannabinoid system (ECS) is a vital biological network essential for maintaining homeostasis and supporting various physiological functions. It…
Recent advances (2022–2024) in eye-tracking for Parkinson’s disease: a promising tool for diagnosing and monitoring symptoms
Abstract Introduction: Parkinson’s disease (PD) is one of the most prevalent neurodegenerative disorders, characterized by both motor and non-motor symptoms,…
Preventive beneficial effects of cannabidiol in a reserpine-induced progressive model of parkinsonism
Abstract Introduction: Parkinson’s disease (PD) is characterized by motor and non-motor symptoms such as tremors, difficulty in initiating movements, depression,…
Neurofilament Light Chain in Cerebrospinal Fluid and Blood in Multiple System Atrophy: A Systematic Review and Meta-Analysis
Abstract Background/Objectives: Multiple system atrophy (MSA) presents a challenging diagnosis due to its clinical overlap with other neurodegenerative disorders, especially…
Low doses of cannabis extract ameliorate non-motor symptoms of Parkinson’s disease patients: a case series
Keywords: cannabis, THC, CBD, Parkinson’s disease, cognition, insomnia, sleepiness, case series Authors: Ana Carolina Ruver-Martins, Ingrid Andrea Rodriguez Martinez, Vinicius…
Diagnosis and treatment of autonomic failure, pain and sleep disturbances in Parkinson’s disease: guideline “Parkinson’s disease” of the German Society of Neurology
Abstract Background and objective: Non-motor symptoms frequently develop throughout the disease course of Parkinson’s disease (PD), and pose affected individuals…
Identification and In Vitro and In Vivo Characterization of KAC-50.1 as a Potential α-Synuclein PET Radioligand
Abstract The accumulation of aggregated α-synuclein (α-syn) is a pathological hallmark of Parkinson’s disease (PD) and other synucleinopathies. Here within,…
Investigation in the cannabigerol derivative VCE-003.2 as a disease-modifying agent in a mouse model of experimental synucleinopathy
Abstract Background: The cannabigerol derivative VCE-003.2, which has activity at the peroxisome proliferator-activated receptor-γ has afforded neuroprotection in experimental models…
CBD’s potential impact on Parkinson’s disease: An updated overview
Abstract Background: Parkinson’s disease (PD) is primarily known as a motor disorder; however, its debilitating non-motor symptoms have a significant…