Aquaporin 4 and the endocannabinoid system: a potential therapeutic target in brain injury
Abstract Brain edema is a critical complication arising from stroke and traumatic brain injury (TBI) with an important impact on…
Neuroprotection
Natural Health Products for Symptomatic Relief of Parkinson’s Disease: Prevalence, Interest, and Awareness
Abstract Background: Natural health products have emerged as a potential symptomatic therapeutic approach for people with Parkinson’s disease (PD). Objective:…
Assessing effects of Cannabis on various neuropathologies: A systematic review
Abstract Natural bioactives possess a wide range of chemical structures that can exert a plethora of pharmacological and toxicological actions,…
Protective Effects of Cannabidiol (CBD) against Qxidative Stress, but Not Excitotoxic-Related Neuronal Cell Damage—An In Vitro Study
Abstract Cannabidiol (CBD) appears to possess some neuroprotective properties, but experimental data are still inconsistent. Therefore, this in vitro study…
Navigating neurological disorders: harnessing the power of natural compounds for innovative therapeutic breakthroughs
Abstract Novel treatments are needed as neurological issues become more frequent worldwide. According to the report, plants, oceans, microorganisms, and…
Cannabis, Cannabinoids, and Stroke: Increased Risk or Potential for Protection—A Narrative Review
Abstract Worldwide, approximately 15 million people per year suffer from stroke. With about 5 million deaths, stroke is the second…
Interactions Between the Ubiquitin–Proteasome System, Nrf2, and the Cannabinoidome as Protective Strategies to Combat Neurodegeneration: Review on Experimental Evidence
Abstract Graphical Abstract: Article type: Review Article Keywords: System interaction, Endocannabinoidome, Ubiquitin–proteasome system, Nrf2/Keap-1/ARE system, Neuroprotection, Neurodegeneration Authors: Luis Angel…
Assessing Cannabidiol as a Therapeutic Agent for Preventing and Alleviating Alzheimer’s Disease Neurodegeneration
Abstract Alzheimer’s disease (AD) is a leading neurodegenerative condition causing cognitive and memory decline. With small-molecule drugs targeting Aβ proving…
The Antioxidant and Neuroprotective Potential of Leaves and Inflorescences Extracts of Selected Hemp Varieties Obtained with scCO2
Abstract Cannabis sativa, a versatile plant with numerous varieties, holds promising potential for a wide range of biological activity. As…
Clinical trials of new drugs for Alzheimer disease: a 2020–2023 update
Abstract Alzheimer’s disease (AD) is the leading cause of dementia, presenting a significant unmet medical need worldwide. The pathogenesis of…