Alternative Treatment of the Resistant-to-Treatment Tourette Syndrome—A Systematic Review
Abstract Background: Tourette syndrome (TS) is a chronic neurodevelopmental disorder with a significant rate of patients remaining refractory to standard…
neurodevelopmental disorders
Carvone derived cannabidiol enantiomers as novel anticonvulsants
Abstract Developmental epilepsy syndromes are characterized by recurrent seizures and developmental delays. Current anticonvulsants target γ-aminobutyric acid type A receptor…
Maternal immune activation followed by peripubertal stress combinedly produce reactive microglia and confine cerebellar cognition
Abstract The functional alteration of microglia arises in brains exposed to external stress during early development. Pathophysiological findings of neurodevelopmental…
Neural basis of adolescent THC-induced potentiation of opioid responses later in life
Abstract Use of one addictive drug typically influences the behavioral response to other drugs, either administered at the same time…
Evaluation of the Efficacy of a Full-Spectrum Low-THC Cannabis Plant Extract Using In Vitro Models of Inflammation and Excitotoxicity
Abstract Evidence has accumulated that Cannabis-derived compounds have the potential to treat neuroinflammatory changes present in neurodevelopmental conditions such as…
Quality of life and associated factors among primary caregivers of children and adolescents with neurodevelopmental disorders attending public hospitals in Addis Ababa, Ethiopia: a cross-sectional study
Abstract Background: Neurodevelopmental disorders are a set of disorders that negatively affect the acquisition of skills in a variety of…
Endocannabinoid System Changes throughout Life: Implications and Therapeutic Potential for Autism, ADHD, and Alzheimer’s Disease
Abstract The endocannabinoid system has been linked to various physiological and pathological processes, because it plays a neuromodulator role in…
The potential for medicinal cannabis to help manage challenging behaviour in people with intellectual disability: A perspective review
Abstract Background: Around 2% of the population have intellectual disabilities. Over one-third people with intellectual disabilities (PwID) present with ‘challenging…
Early Administration of the Phytocannabinoid Cannabidivarin Prevents the Neurobehavioral Abnormalities Associated with the Fmr1-KO Mouse Model of Fragile X Syndrome
Abstract Phytocannabinoids, including the non-addictive cannabis component cannabidivarin (CBDV), have been reported to hold therapeutic potential in several neurodevelopmental disorders…
Redox Imbalance in Neurological Disorders in Adults and Children
Abstract Oxygen is a central molecule for numerous metabolic and cytophysiological processes, and, indeed, its imbalance can lead to numerous…