Medicinal Cannabis for Paediatric Developmental, Behavioural and Mental Health Disorders
Abstract Parents of children with developmental, behavioural and mental health disorders are increasingly asking whether medicinal cannabis might be a…
neurodevelopmental disorders
El papel de los cannabinoides en los trastornos del neurodesarrollo de niños y adolescentes
Abstract Introducción.: Los trastornos del neurodesarrollo tienen una etiología multifactorial que resulta de la interacción entre factores biológicos y ambientales.…
A Placebo-Controlled Trial of Cannabinoid Treatment for Disruptive Behavior in Children and Adolescents with Autism Spectrum Disorder: Effects on Sleep Parameters as Measured by the CSHQ
Abstract Autism spectrum disorder (ASD) is often associated with debilitating sleep disturbances. While anecdotal evidence suggests the positive effect of…
Endocannabinoid System Unlocks the Puzzle of Autism Treatment via Microglia
Abstract Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder and characterized by early childhood-onset impairments in social interaction and…
FMR1 and Autism, an Intriguing Connection Revisited
Abstract Autism Spectrum Disorder (ASD) represents a distinct phenotype of behavioral dysfunction that includes deficiencies in communication and stereotypic behaviors.…
Is Cannabidiol During Neurodevelopment a Promising Therapy for Schizophrenia and Autism Spectrum Disorders?
Abstract Schizophrenia and autism spectrum disorders (ASD) are psychiatric neurodevelopmental disorders that cause high levels of functional disabilities. Also, the…
Cannabinoid treatment for autism: a proof-of-concept randomized trial
Abstract Background: Endocannabinoid dysfunction in animal models of autism spectrum disorder (ASD) and accumulating, albeit anecdotal, evidence for efficacy in…
Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction
Abstract We tested whether cannabinoids (CBs) potentiate alcohol-induced birth defects in mice and zebrafish, and explored the underlying pathogenic mechanisms…
Dysregulated mTORC1-Dependent Translational Control: From Brain Disorders to Psychoactive Drugs
Abstract In the last decade, a plethora of studies utilizing pharmacological, biochemical, and genetic approaches have shown that precise translational…