NK Cell Induced T Cell Anergy Depends on GRAIL Expression
Abstract NK cells (natural killer cells) being a part of the innate immune system have been shown to be involved…
Multiple sclerosis
Glial Cell AMPA Receptors in Nervous System Health, Injury and Disease
Abstract Glia form a central component of the nervous system whose varied activities sustain an environment that is optimised for…
Daily Practice Managing Resistant Multiple Sclerosis Spasticity With Delta-9-Tetrahydrocannabinol: Cannabidiol Oromucosal Spray: A Systematic Review of Observational Studies
Abstract Background/purpose: Spasticity is one of the most common symptoms in people with multiple sclerosis (MS). Conventional anti-spasticity agents have…
The potential effects of hemp seed/evening primrose oils on the mammalian target of rapamycin complex 1 and interferon-gamma genes expression in experimental autoimmune encephalomyelitis
Abstract The mammalian target of rapamycin (mTOR) has a fundamental role in the metabolism, growth, and regulation of the immune…
A Review of Herbal Therapy in Multiple Sclerosis
Abstract Multiple sclerosis is a complex autoimmune disorder which characterized by demyelination and axonal loss in the central nervous system…
Exploiting the Multifaceted Effects of Cannabinoids on Mood to Boost Their Therapeutic Use Against Anxiety and Depression
Abstract The endocannabinoid system (ECS) has been recently recognized as a prominent promoter of the emotional homeostasis, mediating the effects…
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis
Abstract Recent findings highlight the emerging role of the endocannabinoid system in the control of symptoms and disease progression in…
Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells
Abstract Multiple sclerosis (MS) is a chronic debilitating autoimmune disease without a cure. While the use of marijuana cannabinoids for…
Pain Modulation after Oromucosal Cannabinoid Spray (SATIVEX®) in Patients with Multiple Sclerosis: A Study with Quantitative Sensory Testing and Laser-Evoked Potentials
Abstract Background. Delta-9-tetrahydrocannabinol (THC)/cannabidiol (CBD) (nabiximols or Sativex®) is an oromucosal spray formulation containing THC and CBD at an approximately…
Therapeutic potential of medicinal marijuana: an educational primer for health care professionals
Abstract With the proposed Canadian July 2018 legalization of marijuana through the Cannabis Act, a thorough critical analysis of the…