Perspectives on Cannabis-Based Therapy of Multiple Sclerosis: A Mini-Review
Abstract The consistency, efficacy, and safety of cannabis-based medicines have been demonstrated in humans, leading to the approval of the…
Multiple sclerosis
Cannabinoids in Chronic Non-Cancer Pain: A Systematic Review and Meta-Analysis
Abstract Background: For patients with chronic, non-cancer pain, traditional pain-relieving medications include opioids, which have shown benefits but are associated…
Dose-dependent effect of cannabinoid WIN-55,212-2 on myelin repair following a demyelinating insult
Abstract Dysfunctions in the endocannabinoid system have been associated with experimental animal models and multiple sclerosis patients. Interestingly, the endocannabinoid…
Cannabis-based product use in a multiple sclerosis cohort
Abstract Objective: The objective of this study was to characterize the use of cannabis-based products (CBPs) by multiple sclerosis (MS)…
Combination of Cannabinoids, Δ9- Tetrahydrocannabinol and Cannabidiol, Ameliorates Experimental Multiple Sclerosis by Suppressing Neuroinflammation Through Regulation of miRNA-Mediated Signaling Pathways
Abstract Multiple sclerosis (MS) is a chronic and disabling disorder of the central nervous system (CNS) characterized by neuroinflammation leading…
NK Cell Induced T Cell Anergy Depends on GRAIL Expression
Abstract NK cells (natural killer cells) being a part of the innate immune system have been shown to be involved…
Glial Cell AMPA Receptors in Nervous System Health, Injury and Disease
Abstract Glia form a central component of the nervous system whose varied activities sustain an environment that is optimised for…
Daily Practice Managing Resistant Multiple Sclerosis Spasticity With Delta-9-Tetrahydrocannabinol: Cannabidiol Oromucosal Spray: A Systematic Review of Observational Studies
Abstract Background/purpose: Spasticity is one of the most common symptoms in people with multiple sclerosis (MS). Conventional anti-spasticity agents have…
The potential effects of hemp seed/evening primrose oils on the mammalian target of rapamycin complex 1 and interferon-gamma genes expression in experimental autoimmune encephalomyelitis
Abstract The mammalian target of rapamycin (mTOR) has a fundamental role in the metabolism, growth, and regulation of the immune…
A Review of Herbal Therapy in Multiple Sclerosis
Abstract Multiple sclerosis is a complex autoimmune disorder which characterized by demyelination and axonal loss in the central nervous system…