Unveiling the multifaceted role of the FLNC gene: implications for cancer diagnosis and prognosis
Abstract Background: The Filamin C (FLNC) gene, pivotal for cellular structure and function, holds significance in cancer biology. Methods: We…
Kaplan-Meier survival analysis
SurvDB: Systematic Identification of Potential Prognostic Biomarkers in 33 Cancer Types
Abstract The identification of cancer prognostic biomarkers is crucial for predicting disease progression, optimizing personalized therapies, and improving patient survival.…
The Prognostic Significance of NEDD9 Expression in Human Cancers: A Systematic Review, Meta-Analysis, and Omics Exploration
Abstract Background: Neural precursor cell expressed developmentally downregulated 9 (NEDD9) is considered an important factor in the progression of cancer,…
Deep contrastive learning for predicting cancer prognosis using gene expression values
Abstract Recent advancements in image classification have demonstrated that contrastive learning (CL) can aid in further learning tasks by acquiring…
Pan-cancer analysis reveals PDK family as potential indicators related to prognosis and immune infiltration
Abstract Pyruvate dehydrogenase kinases (PDKs) play a key role in glucose metabolism by exerting negative regulation over pyruvate dehyrogenase complex…
PathExpSurv: pathway expansion for explainable survival analysis and disease gene discovery
Abstract Background: In the field of biology and medicine, the interpretability and accuracy are both important when designing predictive models.…
Prognostic and immunological role of acetaldehyde dehydrogenase 1B1 in human tumors: A pan-cancer analysis
Abstract Acetaldehyde dehydrogenases (ALDH) 1B1 is associated with a poor prognosis in pancreatic cancer, colorectal cancer, and osteosarcoma. Overexpression of…
Pan-cancer analysis reveals that G6PD is a prognostic biomarker and therapeutic target for a variety of cancers
Abstract Background: Despite accumulating evidence revealing that Glucose-6-phosphate dehydrogenase (G6PD) is highly expressed in many tumor tissues and plays a…
The Predictive Competing Endogenous RNA Regulatory Networks and Potential Prognostic and Immunological Roles of Cyclin A2 in Pan-Cancer Analysis
Abstract Although accumulating evidence has verified the relationship between CCNA2 and cancers, no pan-cancer analysis about the function and the…
An integrated approach to identify bimodal genes associated with prognosis in câncer
Abstract Bimodal gene expression (where a gene expression distribution has two maxima) is associated with phenotypic diversity in different biological…