Integrative Pan-Cancer Analysis Confirmed that FCGR3A is a Candidate Biomarker Associated With Tumor Immunity
Abstract Background: Fc gamma receptor 3A (FCGR3A) encodes a receptor for the Fc portion of immunoglobulin G, which plays a…
immune infiltration
Distinct Roles of Adenosine Deaminase Isoenzymes ADA1 and ADA2: A Pan-Cancer Analysis
Abstract Objective: Adenosine deaminase (ADA) plays an important role in immune response, which includes two isoenzymes: ADA1 and ADA2. This…
Comprehensive analyses reveal the carcinogenic and immunological roles of ANLN in human cancers
Abstract Background: Anillin (ANLN) is an actin-binding protein that is essential for cell division and contributes to cell growth and…
RecQ mediated genome instability 2 (RMI2): a potential prognostic and immunological biomarker for pan-cancers
Abstract Background: RecQ mediated genome instability 2 (RMI2) is an essential component of the BLM-TopoIIIa-RMI1-RMI2 (BTR) complex. However, the mysterious…
The oncogenic role of tubulin alpha-1c chain in human tumours
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12885-022-09595-0. Article type: Research Article Keywords: TUBA1C, Pancancer, Tumour…
Pan-Cancer Analyses Reveal Oncogenic and Immunological Role of PLOD2
Abstract Some previous studies have shown that PLOD2 has some value in tumorigenesis. However, the broad significance of PLOD2 has…
A Systematic Pan-Cancer Analysis of CASP3 as a Potential Target for Immunotherapy
Abstract CASP3 is the gene encoding caspase-3, a specific protease that cleaves substrates such as poly-ADP ribose polymerase and acetyl-DEVD-7-amino-4-methylcoumarin.…
Prognostic and Immunotherapeutic Roles of KRAS in Pan-Cancer
Abstract KRAS is one well-established tumor-driver gene associated with cancer initiation, development, and progression. Nonetheless, comparative studies of the relevance…
LAMP2 as a Biomarker Related to Prognosis and Immune Infiltration in Esophageal Cancer and Other Cancers: A Comprehensive Pan-Cancer Analysis
Abstract Esophageal cancer (ESCA) is a common malignant tumor with poor prognosis. Accumulating evidence indicates an important role of lysosomal-associated…
Pan-cancer analyses reveal the regulation and clinical outcome association of PCLAF in human tumors
Abstract Studies have shown that PCNA clamp associated factor (PCLAF) plays a paramount role in a variety of cancers; however,…