The role of CRYAB in tumor prognosis and immune infiltration: A Pan-cancer analysis
Abstract Purpose: There is evidence that the Crystallin Alpha B (CRYAB) gene is involved in the regulation of the tumor…
immune cells within the tumor microenvironment
Cannabinoid receptor 2 plays a pro-tumorigenic role in non-small cell lung cancer by limiting anti-tumor activity of CD8+ T and NK cells
Abstract Cannabinoid (CB) receptors (CB1 and CB2) are expressed on cancer cells and their expression influences carcinogenesis in various tumor…
A pan-cancer landscape of IGF2BPs and their association with prognosis, stemness and tumor immune microenvironment
Abstract Background: The human insulin-like growth factor 2 mRNA binding proteins 1–3 (IGF2BP1–3, also called IMP1–3) play essential roles in…
DEF6 has potential to be a biomarker for cancer prognosis: A pan-cancer analysis
Abstract Introduction: DEF6 is a gene associated with the immune system and is thought to play a crucial role in…
S100A11: A Potential Carcinogen and Prognostic Marker That Correlates with the Immunosuppressive Microenvironment in Pan-Cancer
Abstract S100 calcium-binding protein A11 (S100A11) has been proved to be an oncogene of most tumors. However, its role in…
A pan-cancer analysis identifies SOAT1 as an immunological and prognostic biomarker
Abstract Sterol o-acyltransferase1 (SOAT1) is an enzyme that regulates lipid metabolism. Nevertheless, the predictive value of SOAT1 regarding immune responses…
Single-cell analysis of multiple cancer types reveals differences in endothelial cells between tumors and normal tissues
Abstract Endothelial cells (ECs) play an important role in tumor progression. Currently, the main target of anti-angiogenic therapy is the…
Prognostic and Immunological Implications of FAM72A in Pan-Cancer and Functional Validations
Abstract The family with sequence similarity 72 Member A (FAM72A) is overexpressed in several types of cancer. However, its contributions…
Prognostic Values of METTL3 and Its Roles in Tumor Immune Microenvironment in Pan-Cancer
Abstract Background: N6-methyladenosine (m6A) is among the most prevalent RNA modifications regulating RNA metabolism. The roles of methyltransferase-like 3 (METTL3),…
Pan-Cancer Landscape of NEIL3 in Tumor Microenvironment: A Promising Predictor for Chemotherapy and Immunotherapy
Abstract Simple Summary: A reliable efficacy predictor for immunotherapy is warranted due to its unsatisfying responsive rate among cancer patients.…