KRAS is a prognostic biomarker associated with diagnosis and treatment in multiple cancers
Abstract KRAS encodes K-Ras proteins, which take part in the MAPK pathway. The expression level of KRAS is high in…
Immune cell infiltration
Comprehensive analysis of tumor necrosis factor-α-inducible protein 8-like 2 (TIPE2): A potential novel pan-cancer immune checkpoint
Keywords: LAML, Acute Myeloid Leukemia, BLCA, Bladder Urothelial Carcinoma, BRCA, Breast invasive carcinoma, CESC, Cervical squamous cell carcinoma and endocervical…
Pan-cancer analysis of forkhead box Q1 as a potential prognostic and immunological biomarker
Abstract Forkhead box Q1 (FOXQ1) is a member of the forkhead transcription factor family involved in the occurrence and development…
Pan-cancer analysis identifies YTHDF2 as an immunotherapeutic and prognostic biomarker
Abstract Background: N6-methyladenosine (m6A) modification is a dynamic and reversible post-transcriptional RNA modification prevalent in eukaryotic cells. YT521-B homology domain…
High expression of RRM2 mediated by non-coding RNAs correlates with poor prognosis and tumor immune infiltration of hepatocellular carcinoma
Abstract Hepatocellular carcinoma (HCC) is known to have a poor prognosis. Accumulating evidence indicates that RRM2 plays a critical role…
Oncogenetic Function and Prognostic Value of DNA Topoisomerase II Alpha in Human Malignances: A Pan-Cancer Analysis
Abstract Increasing studies have revealed significant associations between TOP2A with oncogenesis and prognosis of human cancers; however, pan-cancer analysis has…
Comprehensive Pan-Cancer Analysis of TRPM8 in Tumor Metabolism and Immune Escape
Abstract Background: Transient receptor potential melastatin 8 (TRPM8) modulates tumor biology and sensitivity to treatment. The present study aimed to…
Roles of Cadherin2 in Thyroid Cancer
Abstract Background: The majority of drug-resistant cells in Thyroid cancer (THCA) tend to exhibit an Epithelial mesenchymal transition (EMT) phenotype,…
Pan-Cancer Integrated Analysis Identification of SASH3, a Potential Biomarker That Inhibits Lung Adenocarcinoma Progression
Abstract Sterile alpha motif (SAM) and Src homology-3 (SH3) domain-containing 3 (SASH3) is an adaptor protein expressed mainly in lymphocytes,…
High Expression of EZH2 Mediated by ncRNAs Correlates with Poor Prognosis and Tumor Immune Infiltration of Hepatocellular Carcinoma
Abstract Background: Hepatocellular carcinoma (HCC) is the predominant form of liver cancer and is accompanied by a complex regulatory network.…