Analysis of Pan-Cancer Revealed the Immunological and Prognostic Potential of CBX3 in Human Tumors
Abstract Chromobox protein homolog 3 (CBX3) has been recognized as a member of the heterochromatin protein 1 family and participate…
Immune cell infiltration
Guanylate-Binding Protein 1 as a Potential Predictor of Immunotherapy: A Pan-Cancer Analysis
Abstract Background: Mainstream application of cancer immunotherapy is hampered by the low response rate of most cancer patients. A novel…
Comprehensive Analysis of the Prognostic and Immunological Role of PAFAH1B in Pan-Cancer
Abstract Platelet-activating factor acetylhydrolase 1B3 (PAFAH1B3) plays a critical role in cancer initiation, metastasis, and progression; however, it remains unknown…
Pan-Cancer Analysis Reveals the Multidimensional Expression and Prognostic and Immunologic Roles of VSTM2L in Cancer
Abstract Immunotherapy can improve survival in a variety of cancers by modulating the interaction between tumors and the tumor immune…
An Integrated Pan-Cancer Analysis of 33 Human Cancers Reveals the Potential Clinical Implications and Immunotherapeutic Value of C-X-C Motif Chemokine Ligand 13
Abstract Background: C-X-C Motif Chemokine Ligand 13 (CXCL13) plays a crucial part in the pathogenesis of numerous lymphoproliferative disorders, inflammatory…
TMC5 is Highly Expressed in Human Cancers and Corelates to Prognosis and Immune Cell Infiltration: A Comprehensive Bioinformatics Analysis
Abstract Background: The oncological role of TMC5 in human cancers has only been revealed partially. We performed integrated bioinformatics analysis…
Differential Expression of the TLR4 Gene in Pan-Cancer and Its Related Mechanism
Abstract Previous studies have revealed the relationship between toll-like receptor 4 (TLR4) polymorphisms and cancer susceptibility. However, the relationship between…
A pan-cancer analysis of the expression of gasdermin genes in tumors and their relationship with the immune microenvironment
Abstract Background: Gasdermins (GSDMs) are a class of proteins related to pyrolysis and in humans, consist of GSDMA, GSDMB, GSDMC,…
METTL7B is a novel prognostic biomarker of lower-grade glioma based on pan-cancer analysis
Abstract Methyltransferase-like 7B (METTL7B) is a member of the methyltransferase-like protein family that plays an important role in the development…
Reconstruction and Analysis of the Immune-Related LINC00987/A2M Axis in Lung Adenocarcinoma
Abstract Enhancer RNAs (eRNAs) participate in tumor growth and immune regulation through complex signaling pathways. However, the immune-related function of…