Abstract Cannabidiol (CBD) decreases seizures in patients with severe pediatric-onset epilepsies including Dravet, Lennox-Gastaut, and Tuberous Sclerosis syndromes. However, the…
Abstract Background: Dysregulation of the endocannabinoid system (eCBS) and the loss of CB1 receptors (CB1R) in the basal ganglia are…
Abstract Cannabis vaping, particularly involving cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC), rapidly delivers highly concentrated cannabinoids to the brain, potentially affecting…
Abstract The expanding legalization of cannabis raises significant public health concerns about its use during pregnancy, particularly due to the…
Abstract Background: Recent preclinical studies have shown sex-dependent antidepressant-like responses of cannabidiol in adolescence, which were dependent on biological sex,…
Abstract Aging is associated with cognitive decline, and currently, there are no approved medications that can prevent these impairments. Recently,…
Abstract Hippocampal encephalitis (HE), or more generally limbic encephalitis, can be secondary to various etiologies. Through this case, we report…
Abstract Synthetic cannabinoid use raises concerns about its neuroinflammatory effects, including molecular adaptations of the endocannabinoid system (ECS) in the…
Abstract Deficits in learning and memory are some of the most commonly reported symptoms following a traumatic brain injury (TBI).…
Abstract A combination of Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) at non-psychoactive doses was previously demonstrated to reduce cognitive decline in…