Nanotechnology for the Efficacious Delivery of Medicinal Cannabis and Pharmaceutical Medicines
Abstract The application of nanoparticles as nanomedicines, particularly for the targeted and efficacious delivery of drugs is an expanding platform…
gut microbiome
The endocannabinoidome–gut microbiome–brain axis as a novel therapeutic target for autism spectrum disorder
Abstract Introduction: Autism spectrum disorder (ASD) is characterized by disruption of the gut–brain axis, which leads to behavioral, psychiatric, metabolic…
Pharmacogenomic and Pharmacomicrobiomic Aspects of Drugs of Abuse
Abstract Background/Objectives: This review examines the role of pharmacogenomics in individual responses to the pharmacotherapy of various drugs of abuse,…
Targeting the Endocannabinoidome: A Novel Approach to Managing Extraintestinal Complications in Inflammatory Bowel Disease
Abstract Background: Inflammatory bowel disease (IBD) is a chronic inflammatory disorder marked by persistent gastrointestinal inflammation and a spectrum of…
The promising role of nanopore sequencing in cancer diagnostics and treatment
Abstract Cancer arises from genetic alterations that impact both the genome and transcriptome. The utilization of nanopore sequencing offers a…
The effects of AG1® supplementation on the gut microbiome of healthy adults: a randomized, double-blind, placebo-controlled clinical trial
Abstract Background: This study aimed to examine the effect of a commercially available multi-ingredient powder (AG1Ⓡ) on the gut microbiome…
The Modulatory Effects and Therapeutic Potential of Cannabidiol in the Gut
Abstract Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that exists in the Cannabis sativa plant. CBD has been found to…
Cannabis use, oral dysbiosis, and neurological disorders
Abstract Cannabis (marijuana) is a leafy plant that has medical, recreational, and other uses. Cannabis is socially accepted and widely…
Hemp hull fiber and two constituent compounds, N-trans-caffeoyltyramine and N-trans-feruloyltyramine, shape the human gut microbiome in vitro
Abstract Mounting evidence supports the potential of dietary bioactives to reduce chronic disease risk. N-trans-caffeoyltyramine (NCT) and N-trans-feruloyltyramine (NFT) have…
Buds and Bugs: A Fascinating Tale of Gut Microbiota and Cannabis in the Fight against Cancer
Abstract Emerging research has revealed a complex bidirectional interaction between the gut microbiome and cannabis. Preclinical studies have demonstrated that…