NKD2 Trigger NF-κB Signaling Pathway and Facilitates Thyroid Cancer Cell Proliferation
Abstract NKD inhibitor of WNT signaling pathway 2 (NKD2) is an emerging player in cancer onset and progression. Here, it…
GSEA
TSPAN4 is a prognostic and immune target in Glioblastoma multiforme
Abstract Background: Atherosclerosis can impact cancer progression due to the cholesterol and calcium metabolism, illustrating the links between atherosclerosis and…
Integrative Analysis of Proteome-wide Association Studies and Functional Enrichment Analysis to Identify Genes and Chemicals Associated with Alcohol Dependence
Abstract Methods: Using data from published alcohol dependence genome-wide association studies, we first conducted a proteome-wide association study of alcohol…
Arylsulfatase I is a prognostic biomarker for head and neck squamous cell carcinoma and Pan‐cancer
Abstract Background: Sulfatase gene family members mediate various biological functions in tumor stroma and tumor cell environments. However, the expressions…
Identifies microtubule-binding protein CSPP1 as a novel cancer biomarker associated with ferroptosis and tumor microenvironment
Keywords: TME, tumor microenvironment, CAF, cancer-associated fibroblasts, EMT, epithelial-mesenchymal transition, DLBC, diffuse large B-cell lymphoma, TCGA, The Cancer Genome Atlas,…
Identification of SHCBP1 as a potential biomarker involving diagnosis, prognosis, and tumor immune microenvironment across multiple cancers
Keywords: AUC, area under the curve, CCLE, cancer cell line encyclopedia, HR, hazard ratio, ROC, receiver operating characteristic, SHCBP1, Shc…
Siglec-9, a Putative Immune Checkpoint Marker for Cancer Progression Across Multiple Cancer Types
Abstract Siglec-9, a cell surface transmembrane receptor mainly expressed on B cells, CD56+ NK cells, and CD4+ and CD8+ T…
ANXA1 (Annexin A1) regulated by MYC (MYC proto-oncogene) promotes the growth of papillary thyroid carcinoma
Abstract Thyroid carcinoma is one of the most common endocrine malignancies, in which papillary thyroid carcinoma (PTC) is the main…
High DSCC1 Level Predicts Poor Prognosis of Lung Adenocarcinoma
Abstract Purpose: To evaluate the role of DSCC1 in LUAD. Patients and Methods: Based on TCGA and GTEx, the Wilcoxon…
The molecular feature of macrophages in tumor immune microenvironment of glioma patients
Keywords: CDF, cumulative distribution function, CGGA, Chinese Glioma Genome Atlas, CNA, copy number alternations, CNV, copy number variation, CSF-1, colony-stimulating…