Abstract There remains ongoing debate regarding the association of homologous recombination deficiency (HRD) with patient survival across various malignancies, highlighting…
Abstract Cell cycle-dependent protein kinase 12 (CDK12) plays a key role in a variety of carcinogenesis processes and represents a…
Abstract Objective: This study aimed to perform an integrated pan-cancer analysis to characterize the expression patterns, prognostic value, genetic alterations,…
Abstract RPL7L1 was found to be aberrantly overexpressed in multiple tumor types such as LIHC, LUAD, COAD, GBM, BRCA, HNSC…
Abstract Simple Summary: To better understand the potential implications of the cross-talk between RKIP and YY1 in cancer, we comprehensively…
Abstract NUMB has been initially identified as a critical cell fate determinant that modulates cell differentiation via asymmetrical partitioning during…
Abstract Background: G-protein signaling modulator 2 (GPSM2) maintains cell polarization and regulates the cell cycle. Recent studies have shown that…
Abstract Objective: We aimed to investigate the relationship between titin (TTN) gene mutations and thyroid cancer (THCA) and to explore…
Abstract Background: The receptor tyrosine kinase mesenchymal–epithelial transition factor (MET) is frequently altered in cancers and is a common therapeutic…
Abstract Inter-patient molecular heterogeneity is the major declared driver of an expanding variety of anticancer drugs and personalizing their prescriptions.…