Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00018-025-05961-w. Article type: Research Article Keywords: Receptor, cannabinoid, Cannabinoid…
Abstract The opioid crisis and widespread demand for pain management have intensified the search for nonopioid analgesics, placing the CB1…
Abstract Introduction: Synthetic cannabinoid receptor agonists (SCRAs) are a diverse class of new psychoactive substances that have been associated with…
Abstract Background: Frequent cannabis use is associated with a higher risk of developing cannabis use disorder and other adverse consequences.…
Abstract Arrestin-dependent pathways are a central component of G protein-coupled receptor (GPCRs) signaling. However, the molecular processes regulating arrestin binding…
Abstract Simple Summary: Neoplastic processes are accompanied by the reprogramming of cell metabolism and alteration of the balance between endogenous…
Abstract Cannabinoid receptor 1 (CB1) is a therapeutically relevant drug target for controlling pain, obesity, and other central nervous system…
Abstract Neurons integrate inputs over different time and space scales. Fast excitatory synapses at boutons (ms and μm), and slow…
Abstract Human immunodeficiency virus type 1 (HIV-1) is known to provoke microglial immune responses which likely play a paramount role…
Abstract Background and Purpose: Src homology 3‐domain growth factor receptor‐bound 2‐like endophilin interacting protein 1 (SGIP1) interacts with cannabinoid CB1…