Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses
Abstract The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient China and Egypt.…
endocannabinoids
Cannabis use, abuse, and withdrawal: Cannabinergic mechanisms, clinical, and preclinical findings
Keywords: cannabinoids, CUD, endocannabinoids, marijuana, THC, tolerance Authors: Andrew J. Kesner ⚬, David M. Lovinger ⚬ Affiliations: Laboratory for Integrative…
Chronic Pain in Dogs and Cats: Is There Place for Dietary Intervention with Micro-Palmitoylethanolamide?
Abstract Simple Summary: Chronic pain is being increasingly recognized and addressed in small animal practice. The recent recognition that inability…
Endocannabinoid System as Therapeutic Target of PTSD: A Systematic Review
Abstract Post-Traumatic Stress Disorder (PTSD) is a complex disorder involving dysregulation of stress-related hormones and neurotransmitter systems. Research focused on…
Cannabis: A Toxin-Producing Plant with Potential Therapeutic Uses
Abstract For thousands of years, Cannabis sativa has been utilized as a medicine and for recreational and spiritual purposes. Phytocannabinoids…
Elevated Brain Fatty Acid Amide Hydrolase Induces Depressive-Like Phenotypes in Rodent Models: A Review
Abstract Altered activity of fatty acid amide hydrolase (FAAH), an enzyme of the endocannabinoid system, has been implicated in several…
Oxidative Stress and Lipid Mediators Modulate Immune Cell Functions in Autoimmune Diseases
Abstract Autoimmune diseases, including psoriasis, systemic lupus erythematosus (SLE), and rheumatic arthritis (RA), are caused by a combination of environmental…
(Endo)Cannabinoids and Gynaecological Cancers
Abstract Simple Summary: Cancers of the female reproductive system are common and are responsible for a large number of deaths…
Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
Abstract Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is…
The Therapeutic Effectiveness of Full Spectrum Hemp Oil Using a Chronic Neuropathic Pain Model
Abstract Background: Few models exist that can control for placebo and expectancy effects commonly observed in clinical trials measuring ‘Cannabis’…