Terpenoids, Cannabimimetic Ligands, beyond the Cannabis Plant
Abstract Medicinal use of Cannabis sativa L. has an extensive history and it was essential in the discovery of phytocannabinoids,…
endocannabinoids
Involvement of Metabolic Lipid Mediators in the Regulation of Apoptosis
Abstract Apoptosis is the physiological mechanism of cell death and can be modulated by endogenous and exogenous factors, including stress…
Antioxidative and Anti-Inflammatory Properties of Cannabidiol
Abstract Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of Cannabis sativa L. CBD is non-psychoactive but exerts…
Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome
Abstract Lifestyle is a well-known environmental factor that plays a major role in facilitating the development of metabolic syndrome or…
The Endocannabinoid System as a Target in Cancer Diseases: Are We There Yet?
Abstract The endocannabinoid system (ECS) has been placed in the anti-cancer spotlight in the last decade. The immense data load…
Exploiting the Multifaceted Effects of Cannabinoids on Mood to Boost Their Therapeutic Use Against Anxiety and Depression
Abstract The endocannabinoid system (ECS) has been recently recognized as a prominent promoter of the emotional homeostasis, mediating the effects…
The Role of Cannabinoids in the Setting of Cirrhosis
Abstract Although the mortality rates of cirrhosis are underestimated, its socioeconomic burden has demonstrated a significant global impact. Cirrhosis is…
Endocannabinoids in Body Weight Control
Abstract Maintenance of body weight is fundamental to maintain one’s health and to promote longevity. Nevertheless, it appears that the…
Interactions of Cannabinoids With Biochemical Substrates
Abstract Recent decades have seen much progress in the identification and characterization of cannabinoid receptors and the elucidation of the…
Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents
Abstract Cancer is the second leading cause of death in the United States with 1.7 million new cases estimated to…