Recreational Cannabis Use During Human Pregnancy: Its Effects on the Placenta and Endocannabinoid System
Abstract The use of cannabis during pregnancy is increasing, in line with its growing societal acceptance and legalization. Cannabis use…
endocannabinoid system
The Effect of SERM/CB2 Receptor Modulators on Repetitive Behaviours in Juvenile and Young Adult Mice May Have Implications for Tourette Syndrome Treatment
Abstract Tourette syndrome (TS) is a neurodevelopmental disorder, with a male-to-female ratio of approximately 3:1, characterised by involuntary tics, frequently…
The dual roles of natural cannabidiol in combating oxidative stress and inflammation: A potential intestinal guardian
Abstract Cannabidiol (CBD), a non-psychoactive and non-addictive phytocannabinoid derived from Cannabis sativa L., has attracted increasing attention for its therapeutic…
The Anti-proliferative Effects of Anandamide and Oleamide in Glioblastoma Cell Lines Recruit Mitochondrial and PPAR-γ Receptor Modulation
Abstract Graphical Abstract: The endocannabinoids AEA, and its related compound ODA, decrease cell viability and proliferation in C6 and RG2…
Self-disturbance in first-episode psychosis: Theoretical framework and potential cannabis interactions – a systematic review
Abstract Cannabis use represents a significant environmental risk factor for psychotic disorders, with emerging evidence suggesting complex interactions between cannabinoid…
The Effect of Cannabidiol on Nociceptive Behaviour and the Endocannabinoid System in an Incisional Wound Model
Abstract Background/Objectives: Wound-related pain is a common, yet inadequately managed condition, and new therapeutic strategies are warranted. Limited data suggests…
Therapeutic Potential for Cannabidiol on Alzheimer’s Disease-Related Neuroinflammation: A Systematic Review and Meta-Analysis
Abstract Alzheimer’s disease (AD) is a pervasive neurodegenerative disorder characterized by chronic neuroinflammation; current interventions primarily offer symptomatic relief. Cannabidiol…
Comparison of clinicopathologic findings and urine drug screen results in cannabis-positive and control dogs
Abstract Introduction: Cannabis intoxication is increasingly reported in small animal practice, often resulting from accidental ingestion of human products or…
Cannabinoid and cannabinoid related receptors in fibroblasts, inflammatory and endothelial cells of the equine hoof with and without laminitis: novel pharmacological target
Abstract Background: Evidence suggests that the endocannabinoid system (ECS) is crucial for regulating inflammation, cell proliferation and pain. The ECS…
Coordinated epigenetic dysregulation of CNR1 and FAAH genes drives endocannabinoid system dysfunction in anorexia nervosa
Abstract Background: Anorexia nervosa (AN) is a severe psychiatric disorder with limited biomarkers for diagnosis and treatment monitoring. We investigated…