TGFBR3 inhibits progression of papillary thyroid cancer by inhibiting the PI3K/AKT pathway and EMT
Abstract Background: Transforming growth factor beta receptor III (TGFBR3) has been shown to play a tumor-suppressive role in a variety…
EMT
High expression of COL8A1 predicts poor prognosis and promotes EMT in papillary thyroid cancer
Abstract Background: Collagen type VIII α 1 chain (COL8A1), a collagen type VIII protein, has been suggested to exert various…
Elevated ITGA3 expression serves as a novel prognostic biomarker and regulates tumor progression in cervical cancer
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-75770-x. Article type: Research Article Keywords: ITGA3, Cervical cancer,…
Prognostic value of EMT-related genes and immune cell infiltration in thyroid carcinoma
Abstract Background: The Epithelial–Mesenchymal Transition (EMT) is a very important process involved in cancer invasion and metastasis. Additionally, the Cathepsin…
Dachsous cadherin related 1 (DCHS1) is a novel biomarker for immune infiltration and epithelial-mesenchymal transition in endometrial cancer via pan-cancer analysis
Abstract Background: Dachsous cadherin related 1 (DCHS1) is one of calcium-dependent adhesion membrane proteins and is mainly involved in the…
Revolutionary multi-omics analysis revealing prognostic signature of thyroid cancer and subsequent in vitro validation of SNAI1 in mediating thyroid cancer progression through EMT
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10238-024-01387-z. Article type: Research Article Keywords: Multi-omics analysis, Thyroid…
Wnt/β-catenin-driven EMT regulation in human cancers
Abstract Graphical abstract: Article type: Review Article Keywords: EMT, Cancer metastasis, Wnt/β-catenin, Chemoresistance, Phytochemicals Authors: Wenhua Xue, Lin Yang, Chengxin…
ID2 promotes tumor progression and metastasis in thyroid cancer
Abstract Background: Inhibitor of DNA Binding 2 (ID2) plays a crucial role in tumor cell proliferation, invasion, metastasis, and stemness.…
HOXD9/miR-451a/PSMB8 axis is implicated in the regulation of cell proliferation and metastasis via PI3K/AKT signaling pathway in human anaplastic thyroid carcinoma
Abstract Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1186/s12967-023-04538-0. Article type: Research Article Keywords: Anaplastic…
CLDN5 identified as a biomarker for metastasis and immune infiltration in gastric cancer via pan-cancer analysis
Abstract Background: CLDN5 protein is essential for the formation of tight junctions in epithelial cells, and has been associated with…