The Role of RKIP in the Regulation of EMT in the Tumor Microenvironment
Abstract Simple Summary: Raf kinase inhibitor protein (RKIP) expression in cancer cells is significantly reduced and promoting cancer cells growth…
EMT
An epithelial-mesenchymal plasticity signature identifies two novel LncRNAs with the opposite regulation
Abstract The epithelial to mesenchymal transition (EMT) is crucial for cancer progression and chemoresistance. EMT is a dynamic process with…
Identifies microtubule-binding protein CSPP1 as a novel cancer biomarker associated with ferroptosis and tumor microenvironment
Keywords: TME, tumor microenvironment, CAF, cancer-associated fibroblasts, EMT, epithelial-mesenchymal transition, DLBC, diffuse large B-cell lymphoma, TCGA, The Cancer Genome Atlas,…
In Vitro Effect of Δ9-Tetrahydrocannabinol and Cannabidiol on Cancer-Associated Fibroblasts Isolated from Lung Cancer
Abstract There is evidence that demonstrates the effect of cannabinoid agonists inhibiting relevant aspects in lung cancer, such as proliferation…
Long non-coding RNA CATIP antisense RNA 1 (lncRNA CATIP-AS1) downregulation contributes to the progression and metastasis of thyroid cancer via epithelial–mesenchymal transition (EMT) pathway
Abstract Thyroid cancer (THCA) is the most common cancer of the endocrine system across the globe. To date, the mechanism…
A Pan-Cancer Analysis of SMARCA4 Alterations in Human Cancers
Abstract Background: SMARCA4, the essential ATPase subunit of SWI/SNF chromatin remodeling complex, regulates transcription through the control of chromatin structure…
A Pan-Cancer Analysis of Cystatin E/M Reveals Its Dual Functional Effects and Positive Regulation of Epithelial Cell in Human Tumors
Abstract Cystatin E/M (CST6), a representative cysteine protease inhibitor, plays both tumor-promoting and tumor-suppressing functions and is pursued as an…
Identification of the EMT-Related Genes Signature for Predicting Occurrence and Progression in Thyroid Cancer
Abstract Background: The detection rate of thyroid cancer (TC) has been continuously improved due to the development of detection technology.…
NR1B2 suppress kidney renal clear cell carcinoma (KIRC) progression by regulation of LATS 1/2-YAP signaling
Abstract Background: Kidney Renal Clear Cell Carcinoma (KIRC) accounts for 75% of all renal cancers. Previous study had conflict evidences…