Comprehensive analysis on the implications of IAH1 in cancer development and progression
Abstract Objective: This study aimed to elucidate the role of the IAH1 gene across multiple cancer types. Methods: Using multi-omics…
Drug sensitivity
Comprehensive multi-omics analysis of CD36 in pan-cancers: Evaluating role in prognosis, immune microenvironment, and therapeutic response
Abstract Cluster of differentiation-36 (CD36) is involved in cellular adhesion, lipid metabolism, immunity, and inflammation. Multiple studies have enlightened the…
YRDC is a Prognostic‐Related Biomarker Correlated With Immune Infiltration and Drug Sensitivity in Pan‐Cancer
Abstract Background: YRDC has emerged as a potential biomarker in cancer, yet its prognostic value, oncogenic mechanisms, role in immune…
Functional characterization and clinical significance of IGSF8 in pan-cancer: an integrated bioinformatic and experimental study
Abstract Background: Immunoglobulin superfamily member 8 (IGSF8) is a membrane protein implicated in crucial biological processes like cell interactions and…
Identification and validation of a novel lymph node metastasis-related model for papillary thyroid carcinoma to predict the prognosis
Abstract Background: Papillary thyroid carcinoma (PTC) is a common malignancy with a good prognosis, but lymph node metastasis (LNM) is…
Identification of novel cholesterol metabolism-related biomarkers for thyroid cancer to predict the prognosis, immune infiltration, and drug sensitivity
Abstract Background: With the sharp increase in the incidence of papillary thyroid carcinoma (PTC), the disease-specific survival rate has not…
CD99 is a potential diagnostic and immunological biomarker in pan-cancer
Abstract Background: As a cell adhesion factor, cluster of differentiation 99 (CD99) mainly plays a role in regulating cell differentiation.…
Pan-cancer profiling of FZD2 as a prognostic biomarker: integrative multi-omics analysis with experimental validation and functional characterization in gastric cancer
Abstract Background: Frizzled class receptor 2 (FZD2), is a critical protein in the Wnt signaling pathway, which plays significant roles…
Characterization of Exhausted T Cell Signatures in Pan-Cancer Settings
Abstract T cells play diverse roles in cancer immunology, acting as tumor suppressors, cytotoxic effectors, enhancers of cytotoxic T lymphocyte…
Comprehensive Analysis of Granzymes and Perforin Family Genes in Multiple Cancers
Abstract Background/Objectives: Cancer remains a significant global health concern, with immunotherapies emerging as promising treatments. This study explored the role…