Comprehensive analysis on the implications of IAH1 in cancer development and progression

Abstract Objective: This study aimed to elucidate the role of the IAH1 gene across multiple cancer types. Methods: Using multi-omics data from public databases including TCGA, GTEx, TIMER, and cBioPortal, we analyzed the expression patterns of IAH1 and their correlations with prognostic outcomes, immune cell infiltration, immune checkpoint markers, tumor mutational burden (TMB), microsatellite instability (MSI), response to immunotherapy, and drug sensitivity through bioinformatic tools and R software. Results: IAH1 expression was significantly upregulated in most cancers and associated with