Abstract Nicotine and cigarette/tobacco use continue to be a prevalent public health issue worldwide. The transition to nicotine addiction occurs…
Abstract Cannabinoids and the endocannabinoid system (ECS) have been intensively studied for their neuroregulatory roles in the central nervous system…
Abstract Pain is a complex phenomenon, and basal ganglia circuitry integrates many aspects of pain including motor, emotional, autonomic, and…
Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects motor and cognition functions. The etiology of Parkinson’s disease…
Abstract Introduction: Migraine is a common and debilitating pain disorder associated with dysfunction of the central nervous system. Advanced magnetic…
Abstract The endocannabinoid system (ECS) plays a key neuromodulatory role in the brain. Main features of endocannabinoids (eCBs) are that…
Abstract Endocannabinoids (eCBs) and the expanded endocannabinoid system (ECS)-“endocannabinoidome”, consists of the endogenous ligands, eCBs, their canonical and non-canonical receptor…
Abstract The prefrontal cortex plays a central role in the control of complex cognitive processes including action control and decision…
Abstract Although the cannabinoid type-2 receptor (CB2) is highly expressed in the immune system, emerging evidence points to CB2 playing…
Abstract Schizophrenia is a chronic mental and behavioral disorder characterized by clusters of symptoms including hallucinations, delusions, disorganized thoughts and…