Self-Normalizing Multi-Omics Neural Network for Pan-Cancer Prognostication
Abstract Prognostic markers such as overall survival (OS) and tertiary lymphoid structure (TLS) ratios, alongside diagnostic signatures like primary cancer-type…
comparative oncology
AURKB and PI3K/AKT/mTOR pathways converge to regulate TERT expression
Abstract Telomere length maintenance, critical for cancer progression, can be driven by TERT promoter mutations (TERTpMUT), which are markers of…
Patterns and factors among oncology fellows recommending medical cannabis to adults with cancer
Abstract Background: Medical cannabis consumption is rising, but limited evidence informs the safety and efficacy of cannabis use in cancer…
NSUN6 expression correlates with prognosis and immune infiltration in human cancers based on pan-cancer analysis
Abstract NSUN6 is a regulator of tRNA methylation that partially exists in the Golgi and centrosomes. It catalyzes the methylation…
Prognostic and immunotherapeutic significance of NCAPD2 in pan-cancer and its role in hepatocellular carcinoma progression via the AKT/GSK-3β signaling pathway
Abstract Present studies indicated that NCAPD2 (Non-SMC condensin I complex subunit D2) has emerged as an essential participant of condensin…
NOX4 as an emerging prognostic and immunological biomarker across pan-cancer analyses
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-03499-2. Article type: Research Article Keywords: NOX4, Pan-cancer, Prognosis,…
Effects of Coronin 2A on prognosis and immune microenvironment in tumor patients: a knowledge map of the novel biomarker via bioinformatics analysis
Abstract Background: Recent studies have highlighted the vital role of CORO2A in tumor proliferation, migration, and metastasis. However, its immunological…
Epigenomic profiling of papillary thyroid carcinoma reveals distinct subtypes with clinical implications
Abstract Papillary thyroid carcinoma (PTC) is the most prevalent form of thyroid cancer with generally favorable outcomes. However, surgeons often…
In silico pan-cancer analysis of VRAC subunits and their prognostic roles in human cancers
Abstract The study focuses on the VRAC channel and its significant roles in cancer development. It addresses a research gap…
Identification of ETV4 as a prognostic biomarker and correlates with immune cell infiltration in head and neck squamous cell carcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-90731-8. Article type: Research Article Keywords: HNSC, Biomarker, ETV4,…