Distinctive chromosomal, mutational and transcriptional profiling in colon versus rectal cancers
Abstract Background: Colorectal cancer (CRC) encompasses tumors arising in the colon (CC) and rectum (RC), often treated as a single…
Colon cancer
ENTR1 affects the progression of colon cancer by regulating energy metabolism under the influence of glycolysis
Abstract Background: Endosome-associated trafficking regulator 1 (ENTR1), also known as Serologically Defined Colon Cancer Antigen 3 (SDCCAG3), was initially identified…
Exploring the Potential of Synthetic Cannabinoids: Modulation of Biological Activity of Normal and Cancerous Human Colon Epithelial Cells
Abstract Colorectal cancer (CRC) is a global problem. Oncology currently practices conventional methods of treating this carcinoma, including surgery, chemotherapy,…
CTHRC1 is associated with BRAF(V600E) mutation and correlates with prognosis, immune cell infiltration, and drug resistance in colon cancer, thyroid cancer, and melanoma
Abstract Colon cancer, thyroid cancer, and melanoma are common malignant tumors that seriously threaten human health globally. The B-Raf proto-oncogene,…
Phytocannabinoids CBD, CBG, and their Derivatives CBD-HQ and CBG-A Induced In Vitro Cytotoxicity in 2D and 3D Colon Cancer Cell Models
Abstract Phytocannabinoids, compounds found in Cannabis sativa L., are used in oncology and palliative care to reduce the adverse reactions…
NXPH4 can be used as a biomarker for pan-cancer and promotes colon cancer progression
Abstract NXPH4 promotes cancer proliferation and invasion. However, its specific role and mechanism in cancer remain unclear. Transcriptome and clinical…
Cannabinoid compounds in combination with curcumin and piperine display an anti-tumorigenic effect against colon cancer cells
Abstract Currently, use of cannabinoids is limited to improve adverse effects of chemotherapy and their palliative administration during treatment is…
Pan-cancer analysis identifies PD-L2 as a tumor promotor in the tumor microenvironment
Abstract Background: Programmed cell death protein 1 (PD-1) receptor has two ligands,programmed death-ligand 1 (PD-L1) and PD-L2. When compared with…
The Synthetic Cannabinoid URB447 Exerts Antitumor and Antimetastatic Effect in Melanoma and Colon Cancer
Abstract The endocannabinoid system is widespread through the body and carries out a wide variety of functions. However, its involvement…
Loss of CHGA Protein as a Potential Biomarker for Colon Cancer Diagnosis: A Study on Biomarker Discovery by Machine Learning and Confirmation by Immunohistochemistry in Colorectal Cancer Tissue Microarrays
Abstract Simple Summary: The identification of effective novel biomarkers is emergently needed in colon cancer patients. In the present study,…