The neuroprotective effect of traditional Chinese medicinal plants—A critical review
Abstract Neurodegenerative and neuropsychiatric diseases are increasingly affecting individuals’ quality of life, thus increasing their cost to social and health…
clinical trials
Measuring the diversity gap of cannabis clinical trial participants compared to people who report using cannabis
Abstract Little is known about the demographics of people who use cannabis, including how use trends within population subgroups have…
Design and Implementation of a Culturally-Tailored Randomized Pilot Trial: Puerto Rican Optimized Mediterranean-Like Diet
Abstract Background: Adhering to a Mediterranean Diet (MedDiet) is associated with a healthier cardiometabolic profile. However, there are limited studies…
Therapeutic Effects of Cannabinoids and Their Applications in COVID-19 Treatment
Abstract Cannabis sativa is one of the first medicinal plants used by humans. Its medical use remains controversial because it…
Promising candidates from drug clinical trials: Implications for clinical treatment of Alzheimer’s disease in China
Abstract Alzheimer’s disease is the most common neurodegenerative disease. Prior to 2017, National Medical Products Administration approved only four drugs…
Role of Cannabidiol for Improvement of the Quality of Life in Cancer Patients: Potential and Challenges
Abstract There is currently a growing interest in the use of cannabidiol (CBD) to alleviate the symptoms caused by cancer,…
Implications for blinding in clinical trials with THC-containing cannabinoids based on the CANNA-TICS trial
Abstract Randomized double-blind placebo-controlled trials (RCTs) are regarded as the gold standard for clinical trials. While there are established standards…
Study protocol for a phase II, double-blind, randomised controlled trial of cannabidiol (CBD) compared with placebo for reduction of brain neuroinflammation in adults with chronic low back pain
Abstract Introduction: Chronic pain is a debilitating medical problem that is difficult to treat. Neuroinflammatory pathways have emerged as a…
The Use of Psychedelics in the Treatment of Medical Conditions: An Analysis of Currently Registered Psychedelics Studies in the American Drug Trial Registry
Abstract Although early therapeutic research on psychedelics dates back to the 1940s, this field of investigation was met with many…
A Placebo-Controlled Trial of Cannabinoid Treatment for Disruptive Behavior in Children and Adolescents with Autism Spectrum Disorder: Effects on Sleep Parameters as Measured by the CSHQ
Abstract Autism spectrum disorder (ASD) is often associated with debilitating sleep disturbances. While anecdotal evidence suggests the positive effect of…