Cannabis for Medical Use: Analysis of Recent Clinical Trials in View of Current Legislation
Abstract Cannabis has long been regarded as a recreational substance in the Western world. The recent marketing authorization of some…
clinical trials
Cannabidiol on the Path from the Lab to the Cancer Patient: Opportunities and Challenges
Abstract Cannabidiol (CBD), a major non-psychotropic component of cannabis, is receiving growing attention as a potential anticancer agent. CBD suppresses…
Glaucoma Clinical Research: Trends in Treatment Strategies and Drug Development
Abstract Purpose: To investigate the trends and progresses in glaucoma research by searching two major clinical trial registries; clinicaltrials.gov, and…
Pharmacological treatment trials of agitation in Alzheimer’s disease: A systematic review of ClinicalTrials.gov registered trials
Abstract Introduction: There is increasing emphasis on the importance of optimizing and standardizing clinical trials of agitation in Alzheimer’s disease…
Clinical Trials of Cannabidiol for Substance Use Disorders: Outcome Measures, Surrogate Endpoints, and Biomarkers
Abstract Background: Cannabidiol (CBD) is a cannabinoid of potential interest for the treatment of substance use disorders. Our aim was…
Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders
Abstract The potential therapeutic use of some Cannabis sativa plant compounds has been attracting great interest, especially for managing neuropsychiatric…
Toxicological Properties of Δ9-tetrahydrocannabinol and Cannabidiol
Abstract Cannabis sativa L. contains more than 100 phytocannabinoids that can interact with cannabinoid receptors CB1 and CB2. None of…
Management of Cancer Cachexia: Attempting to Develop New Pharmacological Agents for New Effective Therapeutic Options
Abstract Cancer cachexia (CC) is a multifactorial syndrome characterized by systemic inflammation, uncontrolled weight loss and dramatic metabolic alterations. This…
Changing the Tone of Clinical Study Design in the Cannabis Industry
Abstract Cannabis (also known as marijuana) is the most frequently used psychoactive substance globally. Cannabis exerts therapeutic functions for many…
Study protocol for a randomised, double-blind, placebo-controlled study evaluating the Efficacy of cannabis-based Medicine Extract in slowing the disease pRogression of Amyotrophic Lateral sclerosis or motor neurone Disease: the EMERALD trial
Abstract Introduction: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with no known cure and with an average life expectancy…