Self-reported use of cannabidiol as a substitute or adjunct for approved medications
Abstract Objective: To assess the prevalence of CBD use among US adults, identify the health conditions for which CBD is…
Cannabis-drug interactions
Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks
Abstract The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids…
Concomitant use of medical cannabis and drugs associated with risks of interaction in older patients: a longitudinal cohort study
Abstract Background: Cannabinoids interact with multiple drugs, with some interactions having significant clinical effects. Objectives: This study aimed to evaluate…
Safety considerations for patients using cannabis
Abstract Cannabis is the most used federally illicit substance in the United States, yet there is limited knowledge about its…
Drug interactions in a sample of inpatients diagnosed with cannabis use disorder
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00702-025-02884-5. Article type: Research Article Keywords: Cannabis, Cannabis-drug interactions,…
Cannabidiol for Toothache: Ups, Downs, and Regulatory Considerations
Keywords: pulpitis, pain, pharmacology, drug interactions, off-label use, decision-making Authors: K.N. Theken ⚬, E.V. Hersh ⚬ Affiliations: Department of Oral…
AM1172 (a hydrolysis-resistant endocannabinoid analog that inhibits anandamide cellular uptake) reduces the viability of the various melanoma cells, but it exerts significant cytotoxic effects on healthy cells: an in vitro study based on isobolographic analysis
Abstract Background: Despite great advances in our understanding of the impact of cannabinoids on human organism, many of their properties…
The Influence of Cannabidiol on the Pharmacokinetics of Methylphenidate in Healthy Subjects
Abstract Introduction: Cannabidiol (CBD) is a widely utilized nonpsychoactive cannabinoid available as an over-the-counter supplement, a component of medical cannabis,…
Effect of two oral formulations of cannabidiol on responses to emotional stimuli in healthy human volunteers: pharmaceutical vehicle matters
Abstract Objective: To compare plasma concentrations of cannabidiol (CBD) following oral administration of two formulations of the drug (powder and…
Buprenorphine–cannabis interaction in patients undergoing opioid maintenance therapy
Abstract Buprenorphine is a partial μ-opioid agonist widely used for opioid maintenance therapy (OMT). It is mainly metabolized to pharmacologically…