Detrimental Effect of Cannabidiol on the Early Onset of Diabetic Nephropathy in Male Mice
Abstract Anti-inflammatory and antidiabetogenic properties have been ascribed to cannabidiol (CBD). CBD-based medicinal drugs have been approved for over a…
cannabis-derived phytocannabinoids
Sex differences in medical cannabis-related adverse effects
Abstract Supplemental Digital Content is Available in the Text. Women are more susceptible to medical cannabis–related adverse effects because of…
Neuroprotective and Symptomatic Effects of Cannabidiol in an Animal Model of Parkinson’s Disease
Abstract Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia Nigra pars…
Cannabidiol Displays Proteomic Similarities to Antipsychotics in Cuprizone-Exposed Human Oligodendrocytic Cell Line MO3.13
Abstract Cannabidiol, a compound of Cannabis sativa, has been proposed as an alternative treatment of schizophrenia. Preclinical and clinical data…
Prolonged Medical Cannabis Treatment is Associated With Quality of Life Improvement and Reduction of Analgesic Medication Consumption in Chronic Pain Patients
Abstract Introduction: Chronic non-cancer pain (CNCP) is one of the most prevalent indications for medical cannabis (MC) treatment globally. In…
Anti-Bacterial Properties of Cannabigerol Toward Streptococcus mutans
Abstract Streptococcus mutans (S. mutans) is a gram-positive facultatively anaerobic bacterium and the most common pathogen associated with tooth caries.…
Specific Compositions of Cannabis sativa Compounds Have Cytotoxic Activity and Inhibit Motility and Colony Formation of Human Glioblastoma Cells In Vitro
Abstract Simple Summary: Glioblastoma multiforme (GBM) is the most frequent, invasive, and lethal subtype of glioma brain tumors. Cannabis is…
Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Actions of Phytocannabinoids or Endocannabinoids on TRPA1 and TRPV1 Channels
Abstract Introduction:Cannabis sativa produces hundreds of bioactive compounds, including cannabinoids and terpenoids. It has been proposed that cannabinoids act in…
Chronological Review and Rational and Future Prospects of Cannabis-Based Drug Development
Abstract Despite the surge in cannabis chemistry research and its biological and medical activity, only a few cannabis-based pharmaceutical-grade drugs…
Cannabis sativa extracts protect LDL from Cu2+-mediated oxidation
Abstract Background: Multiple therapeutic properties have been attributed to Cannabis sativa. However, further research is required to unveil the medicinal…