Cannabinoid Ligands Targeting TRP Channels
Abstract Transient receptor potential (TRP) channels are a group of membrane proteins involved in the transduction of a plethora of…
cannabinoids
Medicinal Cannabis—Potential Drug Interactions
Abstract The endocannabinoids system (ECS) has garnered considerable interest as a potential therapeutic target in various carcinomas and cancer-related conditions…
New Methods for the Comprehensive Analysis of Bioactive Compounds in Cannabis sativa L. (hemp)
Abstract Cannabis sativa L. is a dioecious plant belonging to the Cannabaceae family. The main phytochemicals that are found in…
Potential Clinical Benefits of CBD-Rich Cannabis Extracts Over Purified CBD in Treatment-Resistant Epilepsy: Observational Data Meta-analysis
Abstract This meta-analysis paper describes the analysis of observational clinical studies on the treatment of refractory epilepsy with cannabidiol (CBD)-based…
Cannabinoids, the Heart of the Matter
Keywords: calcium channel, cannabinoids, cell signaling, drug abuse, drug therapy, heart disease, marijuana, transmembrane spanning receptors, Lifestyle, Cardiovascular Disease, Heart…
Plant-Based Cannabinoids for the Treatment of Chronic Neuropathic Pain
Abstract Chronic neuropathic pain is a prevalent condition that places a heavy burden on individuals and the healthcare system. Current…
Addictive potential of novel treatments for refractory depression and anxiety
Abstract Treatment-resistant mood disorders and anxiety disorders require intensive treatment, but treatment options should balance benefits and adverse effects or…
The Role of Cannabinoids in the Setting of Cirrhosis
Abstract Although the mortality rates of cirrhosis are underestimated, its socioeconomic burden has demonstrated a significant global impact. Cirrhosis is…
A Systematic Review of the Complex Effects of Cannabinoids on Cerebral and Peripheral Circulation in Animal Models
Abstract While cannabis is perceived as a relatively safe drug by the public, accumulating clinical data suggest detrimental cardiovascular effects…
Mechanistic Potential and Therapeutic Implications of Cannabinoids in Nonalcoholic Fatty Liver Disease
Abstract Nonalcoholic fatty liver disease (NAFLD) is comprised of nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH). It is defined…