Cannabis, from plant to pill
Abstract The therapeutic application of cannabis is attracting substantial public and clinical interest. The cannabis plant has been described as…
cannabinoids
Cannabinoids in Glioblastoma Therapy: New Applications for Old Drugs
Abstract Glioblastoma (GBM) is the most malignant brain tumor and one of the deadliest types of solid cancer overall. Despite…
Emerging Role of (Endo)Cannabinoids in Migraine
Abstract In this mini-review, we summarize recent discoveries and present new hypotheses on the role of cannabinoids in controlling trigeminal…
A stimulus-responsive, in situ-forming, nanoparticle-laden hydrogel for ocular drug delivery
Abstract Most medications targeting optic neuropathies are administered as eye drops. However, their corneal penetration efficiencies are typically < 5%.…
The current state and future perspectives of cannabinoids in cancer biology
Abstract To date, cannabinoids have been allowed in the palliative medicine due to their analgesic and antiemetic effects, but increasing…
Psychosocial and pharmacological interventions for the treatment of cannabis use disorder
Abstract Cannabis use has been continuously increasing, and cannabis use disorder (CUD) has become a public health issue. Some psychosocial…
Systematic review and meta‐analysis of cannabinoids in palliative medicine
Abstract We provide a systematic review and meta‐analysis on the efficacy, tolerability, and safety of cannabinoids in palliative medicine. The…
Cannabinoids for Treating Cardiovascular Disorders: Putting Together a Complex Puzzle
Abstract Cannabinoids have been increasingly gaining attention for their therapeutic potential in treating various cardiovascular disorders. These disorders include myocardial…
A randomised controlled cross-over double-blind pilot study protocol on THC:CBD oromucosal spray efficacy as an add-on therapy for post-stroke spasticity
Abstract Introduction: Stroke is the most disabling neurological disorder and often causes spasticity. Transmucosal cannabinoids (tetrahydrocannabinol and cannabidiol (THC:CBD), Sativex)…
A review of oral cannabinoids and medical marijuana for the treatment of chemotherapy-induced nausea and vomiting: a focus on pharmacokinetic variability and pharmacodynamics
Abstract Purpose: Oral cannabinoids (i.e., dronabinol, nabilone) containing the active component of marijuana, delta(Δ)9-tetrahydrocannabinol (THC), are available for the treatment…