Role of Endocannabinoids in Glaucoma: A Review
Abstract Aims: A review of the published literature was done to understand the role of endocannabinoids in glaucoma. Background: As…
cannabinoid receptor 2 (CB2R)
Endocannabinoid system upregulates the enrichment and differentiation of human iPSC- derived spermatogonial stem cells via CB2R agonism
Abstract Background: Male factor infertility (MFI) is responsible for 50% of infertility cases and in 15% of the cases sperm…
Involvement of CB1R and CB2R Ligands in Sleep Disorders and Addictive Behaviors in the Last 25 Years
Abstract Over the last three decades, the decriminalization and legalization of therapeutic and recreational marijuana consumption have increased. Consequently, the…
The antitumor action of endocannabinoids in the tumor microenvironment of glioblastoma
Abstract Approximately 80% of all malignant brain tumors are gliomas, which are primary brain tumors. The most prevalent subtype of…
Cannabinoids and Their Receptors in Skin Diseases
Abstract The therapeutic application of cannabinoids has gained traction in recent years. Cannabinoids interact with the human endocannabinoid system in…
Neuroinflammation in the Central Nervous System: Exploring the Evolving Influence of Endocannabinoid System
Abstract Neuroinflammation is a complex biological process that typically originates as a protective response in the brain. This inflammatory process…
Cannabis Use and Associated Gastrointestinal Disorders: A Literature Review
Abstract Cannabis, commonly known as marijuana, is used by at least 18% of the United States (US) population, which makes…
Cannabinoid Signaling in Kidney Disease
Abstract Endocannabinoid signaling plays crucial roles in human physiology in the function of multiple systems. The two cannabinoid receptors, CB1…
Persistent Diarrhea and Eosinophilic Esophagitis Resulting From Chronic Cannabidiol Usage for Refractory Epilepsy
Abstract Cannabidiol is used in the care of treatment-resistant epilepsy. It has been associated with varying side effects, ranging from…
Cannabinoid receptors in the inflammatory cells of canine atopic dermatitis
Abstract Background: Atopic dermatitis (AD) is one of the most common cutaneous inflammatory and pruritic diseases in dogs. Considering its…