Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer’s disease
Abstract Background: Because of their low levels of expression and the inadequacy of current research tools, CB2 cannabinoid receptors (CB2R)…
cannabinoid CB1 receptor
Behavioral effects of the cannabinoid CB1 receptor allosteric modulator ORG27569 in rats
Abstract The cannabinoid CB1 receptor system is involved in feeding behaviors and the CB1 receptor antagonist SR141716A is an effective…
CB1 cannabinoid receptor stimulation during adolescence impairs the maturation of GABA function in the adult rat prefrontal cortex
Abstract Converging epidemiological studies indicate that cannabis abuse during adolescence increases the risk of developing psychosis and prefrontal cortex (PFC)-dependent…
The endocannabinoid system in anxiety, fear memory and habituation
Abstract Evidence for the involvement of the endocannabinoid system (ECS) in anxiety and fear has been accumulated, providing leads for…
AAV-Mediated Overexpression of the CB1 Receptor in the mPFC of Adult Rats Alters Cognitive Flexibility, Social Behavior, and Emotional Reactivity
Abstract The endocannabinoid (ECB) system is strongly involved in the regulation of cognitive processing and emotional behavior and evidence indicates…
Hippocampal CB1 receptors mediate the memory impairing effects of Δ9-tetrahydrocannabinol
Abstract It is firmly established that the hippocampus, a brain region implicated in spatial learning, episodic memory, and consolidation, contains…