Harmful Effects of Smoking Cannabis: A Cerebrovascular and Neurological Perspective
Abstract Apart from being used as a medicine, cannabis or marijuana is the most widely abused recreational drug all over…
Cannabidiol derivative/ NRF2/ BACH1/ HMOX1/ neurodegenerative diseases
Cannabidiol Regulates the Expression of Keratinocyte Proteins Involved in the Inflammation Process through Transcriptional Regulation
Abstract Cannabidiol (CBD), a natural phytocannabinoid without psychoactive effect, is a well-known anti-inflammatory and antioxidant compound. The possibility of its…
A Systematic Review of the Effectiveness of Medical Cannabis for Psychiatric, Movement and Neurodegenerative Disorders
Abstract The discovery of endocannabinoid’s role within the central nervous system and its potential therapeutic benefits have brought forth rising…
Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agents
Abstract The basic mechanism of the major neurodegenerative diseases, including neurogenic pain, needs to be agreed upon before rational treatments…
Cannabinoids: New Promising Agents in the Treatment of Neurological Diseases
Abstract Nowadays, Cannabis sativa is considered the most extensively used narcotic. Nevertheless, this fame obscures its traditional employ in native…
The Endocannabinoid System: A Putative Role in Neurodegenerative Diseases
Abstract Background: Following the characterization of the chemical structure of D9-tetrahydrocannabinol (THC), the main psychoactive constituent of marijuana, researchers have…
Dysregulated mTORC1-Dependent Translational Control: From Brain Disorders to Psychoactive Drugs
Abstract In the last decade, a plethora of studies utilizing pharmacological, biochemical, and genetic approaches have shown that precise translational…