Analysis of the potential biological value of pyruvate dehydrogenase E1 subunit β in human cancer
Abstract BACKGROUND: The pyruvate dehydrogenase E1 subunit β (PDHB) gene which regulates energy metabolism is located in mitochondria. However, few…
Cancer prognosis
A pan-cancer characterization of immune-related NFIL3 identifies potential predictive biomarker
Abstract Background: Nuclear factor interleukin 3 (NFIL3) mainly focuses on the regulation of the circadian rhythm and immune system. However,…
Aberrant RBMX expression is relevant for cancer prognosis and immunotherapy response
Abstract Cancer accounts for the highest rates of morbidity and mortality worldwide. RNA binding motif protein X-linked (RBMX) is a…
Pan-cancer analysis of SERPINE family genes as biomarkers of cancer prognosis and response to therapy
Abstract Background: Serine protease inhibitor E (SERPINE) family genes participate in the tumor growth, cancer cell survival and metastasis. However,…
Pan-cancer Multi-omics Analysis Reveals HMGN1 as a Potential Prognostic and Immune Infiltration-associated Biomarker
Abstract Background: The High Mobility Group Nucleosomal Binding Domain 1 Gene (HMGN1) is crucial for epigenetic regulation. However, the specific…
Prognostic value and immunological role of PD-L1 gene in pan-cancer
Abstract Objective: PD-L1, a target of immune checkpoint blockade, has been proven to take the role of an oncogene in…
Fibroblast activation protein (FAP) as a prognostic biomarker in multiple tumors and its therapeutic potential in head and neck squamous cell carcinoma
Abstract Background: Fibroblast activation protein (FAP), a cell surface serine protease, plays roles in tumor invasion and immune regulation. However,…
Integrated Multi-omics Analyses Identify CDCA5 as a Novel Biomarker Associated with Alternative Splicing, Tumor Microenvironment, and Cell Proliferation in Colon Cancer Via Pan-cancer Analysis
Abstract Background: CDCA5 has been reported as a gene involved in the cell cycle, however current research provides little details.…
Investigation of the feasibility of NRAV as a biomarker for hepatocellular carcinoma
Abstract The long non-coding RNA, Negative Regulator of Antiviral Response (NRAV) has been identified as a participant in both respiratory…
GLIS1, Correlated with Immune Infiltrates, Is a Potential Prognostic Biomarker in Prostate Cancer
Abstract Prostate cancer (PCa) is a prevalent malignant disease and the primary reason for cancer-related mortality among men globally. GLIS1…