Pan-cancer analysis of prognostic and immunological role of DTYMK in human tumors
Abstract Background: Deoxythymidylate kinase (DTYMK) has been reported to correlate with the progression of hepatocellular carcinoma. However, the role of…
cancer immunotherapy
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy
Abstract The aberrant protein disulfide isomerase A5 (PDIA5) expression was relevant to the poor prognosis of patients with human cancers.…
Pan-cancer analyses confirmed the cuproptosis-related gene FDX1 as an immunotherapy predictor and prognostic biomarker
Abstract Background: The latest research identified cuproptosis as an entirely new mechanism of cell death. However, as a key regulator…
Characterization of Lactate Metabolism Score in Breast and Thyroid Cancers to Assist Immunotherapy via Large-Scale Transcriptomic Data Analysis
Abstract Breast cancer (BC) and thyroid cancer (TC) have the highest rate of incidence, especially in women. Previous studies have…
Targeted Therapeutic Options and Future Perspectives for HER2-Positive Breast Cancer
Abstract Simple Summary: The development of several antiHuman Epidermal Growth Factor Receptor 2 (HER2) treatments over the last few years…
A Pan-Cancer Analysis Revealing the Dual Roles of Lysine (K)-Specific Demethylase 6B in Tumorigenesis and Immunity
Abstract Introduction: Epigenetic-targeted therapy has been increasingly applied in the treatment of cancers. Lysine (K)-specific demethylase 6B (KDM6B) is an…
A SIRPαFc Fusion Protein Conjugated With the Collagen-Binding Domain for Targeted Immunotherapy of Non-Small Cell Lung Cancer
Abstract The SIRPαFc fusion protein can block the immunosuppressive CD47-SIRPα signal between macrophages and tumor cells as a decoy receptor…
A Pan-Cancer Analysis Reveals the Prognostic and Immunotherapeutic Value of ALKBH7
Abstract Recent studies have identified a role for ALKBH7 in the occurrence and progression of cancer, and this protein is…
A Comparative and Comprehensive Review of Antibody Applications in the Treatment of Lung Disease
Abstract Antibodies are a type of protein produced by active B cells in response to antigen stimulation. A series of…
Association of a Novel Prognosis Model with Tumor Mutation Burden and Tumor-Infiltrating Immune Cells in Thyroid Carcinoma
Abstract Although immunotherapy has recently demonstrated a substantial promise in treating advanced thyroid carcinoma (THCA), it is not appropriate for…