Abstract Encapsulated cell-based therapies for solid tumors have shown promising results in pre-clinical settings. However, the inability to culture encapsulated…
Abstract Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is a cell surface antigen for therapeutic targeting in prostate…
Abstract Objective: This study aims to evaluate the prognostic value of m6A-associated long noncoding RNAs (lncRNAs) and their interaction with…
Abstract Cancer development is closely associated with immunosuppressive tumor microenvironment (TME) that attenuates antitumor immune responses and promotes tumor cell…
Abstract Background: Transporter associated with antigen processing 1 (TAP1) is a molecule involved in processing and presentation of major histocompatibility…
Abstract Introduction: Cellular senescence is a hallmark of tumors and has potential for cancer therapy. Cellular senescence of tumor cells…
Abstract Background: PTPN2, a member of the non-receptor protein tyrosine phosphatases family, holds a crucial role in tumorigenesis and cancer…
Keywords: scRNA-seq, Single-cell RNA-sequencing, CAFs, Cancer-associated fibroblasts, HGSOC, High-grade serous ovarian carcinoma, TCGA, The Cancer Genomics Atlas, LUAD, Lung adenocarcinoma,…
Abstract Background: Accumulating evidence suggests that N6-methyladenosine (m6A) RNA methylation plays an important role in tumor proliferation and growth. However,…
Abstract Background: Thyroid cancer (THCA) is the most prevalent malignant disease of the endocrine system, in which 5-year survival can…