Abstract Background and aim: Protein kinase D1 (PRKD1), a serine/threonine kinase, regulates cellular processes such as proliferation, apoptosis, migration, and…
Abstract Gold standard genomic datasets severely under-represent non-European populations, leading to inequities and a limited understanding of human disease. Therapeutics…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-85444-x. Article type: Research Article Keywords: NTN1, Pan-cancer, Biomarker,…
Abstract Branched-chain amino acid transaminase 2 (BCAT2) encodes a crucial protein involved in the initial catalysis of branched-chain amino acid…
Abstract SASH1 (SAM and SH3 domain containing 1) has been increasingly reported as a tumor suppressor gene. However, there is…
Abstract Background and objective: The wingless-related integration site family (WNT) signaling pathway is critical for tumor progression and development. It…
Abstract The APOBEC/AID family is known for its mutator activity, and recent evidence also supports the potential impact of ADARs.…
Abstract Despite past research linking HLF mutations to cancer development, no pan-cancer analyses of HLF have been published. As a…
Abstract Minichromosome Maintenance Complex Component 4 (MCM4) is a vital component of the mini-chromosome maintenance complex family, crucial for initiating…
Abstract Phosphofructokinase, platelet (PFKP) is a rate-limiting enzyme of glycolysis that plays a decisive role in various human physio-pathological processes.…