Bone Targeted Parathyroid Hormone Antagonists for Prevention of Breast Cancer Bone Metastases
Abstract Breast cancer frequently spreads to the bones, leading to pain, fractures, and other bone-related complications. Current treatments slow the…
bone metastasis
Identification and validation of a novel lymph node metastasis-related model for papillary thyroid carcinoma to predict the prognosis
Abstract Background: Papillary thyroid carcinoma (PTC) is a common malignancy with a good prognosis, but lymph node metastasis (LNM) is…
Pan-cancer analysis of oncogenic role of MAGOH and experiment validation in hepatocellular carcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-08678-9. Article type: Research Article Keywords: MAGOH (Mago-nashi homolog),…
ARHGAP36 serves as a diagnostic and therapeutic marker that mediates immune escape and promotes thyroid cancer metastasis
Abstract Thyroid cancer (THCA) is a prevalent malignancy of the head and neck region, yet the mechanisms underlying its tumorigenesis…
Identification of novel prognostic biomarkers for thyroid cancer by integrated transcriptome analysis of metastasis-associated genes
Abstract Introduction: Distant metastasis (DM) is the most important prognostic factor affecting the overall survival (OS) of thyroid cancer. The…
The Role of PAX7 in Breast Cancer Prognosis and Its Mechanistic Involvement in the Wnt/β‐Catenin Pathway
Abstract Breast cancer significantly affects women’s lives globally. While PAX7 (Paired Box 7), a regulatory protein linked to muscle growth,…
Inside a Metastatic Fracture: Molecular Bases and New Potential Therapeutic Targets
Abstract Introduction: Bone metastases and pathological fractures significantly impact the prognosis and quality of life in cancer patients. However, clinical…
Cannabidiol as a novel therapeutic agent in breast cancer: evidence from literature
Abstract Background: Breast cancer is one of the most prevalent cancers worldwide, posing significant challenges due to its heterogeneity and…
Developing a named entity framework for thyroid cancer staging and risk level classification using large language models
Abstract We developed a named entity (NE) framework for information extraction from semi-structured clinical notes retrieved from The Cancer Genome…
System Analysis Identifies MYBL2 As a Novel Oncogene Target for Metastatic Prostate Cancer
Abstract Bone metastasis significantly contributes to the unfavorable prognosis observed in patients with prostate cancer. MYB proto-oncogene like 2 (MYBL2)…