Systematic pan-cancer analysis identifies SLC31A1 as a biomarker in multiple tumor types
Abstract Background: Solute Carrier Family 31 Member 1 (SLC31A1) has recently been identified as a cuproptosis-regulatory gene. Recent studies have…
Biomarker
A pan-cancer analysis reveals CHD1L as a prognostic and immunological biomarker in several human cancers
Abstract Introduction: Several recent studies pointed out that chromodomain-helicase-DNA-binding protein 1-like (CHD1L) is a putative oncogene in many human tumors.…
The cell senescence regulator p16 is a promising cancer prognostic and immune check-point inhibitor (ICI) therapy biomarker
Abstract Cyclin-dependent kinase inhibitor 2A (CDKN2A) encodes the cell senescence regulator protein p16. The expression of p16 raises in cell…
Pan-cancer analysis reveals the associations between MMP13 high expression and carcinogenesis and its value as a serum diagnostic marker
Abstract Background: Matrix metalloproteinase-13 (MMP13) is a member of the endopeptidase matrix metalloproteinase family, which is involved in many normal…
Characterization of SHCBP1 to prognosis and immunological landscape in pan-cancer: novel insights to biomarker and therapeutic targets
Abstract Background: Previous studies have revealed the significant roles of SHC SH2 domain-binding protein 1 (SHCBP1) in occurrence and progression…
KLF4 loss in hepatocellular carcinoma: Improving prognostic prediction and correlating immune infiltrates
Abstract Introduction: Although the molecular mechanisms of Krüpple-like factor 4 (KLF4) as a tumor suppressor in HCC tumorigenesis have been…
The role of fatty acid desaturase 2 in multiple tumor types revealed by bulk and single-cell transcriptomes
Abstract Background: Previous studies have demonstrated the important role of fatty acid desaturase 2 (FADS2) in governing tumorigenesis and tumor…
Association of SMC4 with prognosis and immune infiltration of sarcoma
Abstract Objective: This study was performed to explore the prognostic relevance of structural maintenance of chromosomes 4 (SMC4) in pan-cancer…
NCAPG2 could be an immunological and prognostic biomarker: From pan-cancer analysis to pancreatic cancer validation
Abstract More recently, NCAPG2 has emerged as an intrinsically essential participant of the condensin II complex involved in the process…
ANXA2 is a potential biomarker for cancer prognosis and immune infiltration: A systematic pan-cancer analysis
Abstract Background: Annexin A2 (ANXA2) belongs to the Annexin A family and plays a role in epithelial-mesenchymal transition, fibrinolysis, and…